442847-66-7

Basic information

• Product Name: p-Nitrobenzyl (5R,6S)-2-(diphenylphosphoryloxy)-6-((1R)-1-hydroxyethyl)carbapen-2-em-3-carboxylate
• Synonyms: (5r,6s)-3-[(diphenoxyphosphinyl)oxy]-6-[(1r)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid (4-nitrophenyl)methyl ester;IMIPENEM INTERMEDIATE;N-METHYLPYRROLIDINONESOLVATE;P-NITROBENZYL (1R,5R,6S)-6-[(1R)-1-HYDROXYETHYL]-2-[(DIPHENYLPHOSPHONO)OXY]-CARBAPEN-2-EM-3-CARBOXYLATE;PROTECTED THIENCIN HYDROCHLORIDE;THIENAMYCIN P-NITROBENZYL ESTER HYDROCHLORIDE;thienamycin p-nitrobenzylester hydrochloride (n-methylpyrrolidinonesolvate);(5R,6S)-3-(2-AMINO-ETHYLSULFANYL)-6-((R)-1-HYDROXY-ETHYL)-7-OXO-1-AZA-BICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID 4-NITRO-BENZYL ESTER, HYDROCHLORIDE
• CAS NO: 442847-66-7
• Molecular Formula: C18H22ClN3O6S
• Molecular Weight: 443.9
• Mol File: 442847-66-7.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 645.5°C at 760 mmHg
• Flash Point: 344.2°C
• Appearance: /
• Density: 1.49
• Vapor Pressure: 1.51E-17mmHg at 25°C
• CAS DataBase Reference: p-Nitrobenzyl (5R,6S)-2-(diphenylphosphoryloxy)-6-((1R)-1-hydroxyethyl)carbapen-2-em-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: p-Nitrobenzyl (5R,6S)-2-(diphenylphosphoryloxy)-6-((1R)-1-hydroxyethyl)carbapen-2-em-3-carboxylate(442847-66-7)
• EPA Substance Registry System: p-Nitrobenzyl (5R,6S)-2-(diphenylphosphoryloxy)-6-((1R)-1-hydroxyethyl)carbapen-2-em-3-carboxylate(442847-66-7)

Safety Data

• Hazardous Substances Data: 442847-66-7(Hazardous Substances Data)

Usage

General Description

p-Nitrobenzyl (5R,6S)-2-(diphenylphosphoryloxy)-6-((1R)-1-hydroxyethyl)carbapen-2-em-3-carboxylate is a chemical compound with a complex structure, primarily used in the field of medicinal chemistry. Its structure includes a carbapenem ring, which is a class of antibiotics with a broad spectrum of activity against many bacteria. The compound also contains a nitrobenzyl group, which is often used as a protecting group in organic synthesis to prevent undesired reactions. The presence of a phosphoryloxy group and a hydroxyethyl group suggest potential reactivity with phosphorylating agents and enzymes involved in phosphorylation processes. Overall, the compound's structure and functional groups make it a potentially valuable molecule for the development of new antibiotics or pharmaceuticals with specific biological activities.

InChI:InChI=1/C18H21N3O6S.ClH/c1-10(22)15-13-8-14(28-7-6-19)16(20(13)17(15)23)18(24)27-9-11-2-4-12(5-3-11)21(25)26;/h2-5,10,13,15,22H,6-9,19H2,1H3;1H/t10-,13-,15-;/m1./s1