442850-72-8

Basic information

• Product Name: BUTTPARK 30\09-83
• Synonyms: BUTTPARK 30\09-83;1-TERT-BUTYL-3-PHENYL-1H-PYRAZOL-5-AMINE
• CAS NO: 442850-72-8
• Molecular Formula: C₁₃H₁₇N₃
• Molecular Weight: 215.29
• Mol File: 442850-72-8.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: BUTTPARK 30\09-83(CAS DataBase Reference)
• NIST Chemistry Reference: BUTTPARK 30\09-83(442850-72-8)
• EPA Substance Registry System: BUTTPARK 30\09-83(442850-72-8)

Safety Data

• Hazardous Substances Data: 442850-72-8(Hazardous Substances Data)

Upstream product

• 7400-27-3 tertbutylhydrazine hydrochloride 
• 614-16-4 Benzoylacetonitrile 

Downstream Products

• 1023655-00-6 C₃₂H₃₉N₇O₃S 
• 77493-73-3 4,7-dihydro-2-phenylpyrazolo[1,5-a]pyrimidin-7-one 
• 1603826-70-5 4-phenyl-6H-pyrazolo[3,4-c]isothiazole-3-carboxamide 
• 1603826-68-1 6-(tert-butyl)-4-phenyl-6H-pyrazolo[3,4-c]isothiazole-3-carboxamide 
• 1603826-48-7 4-phenyl-6H-pyrazolo[3,4-c]isothiazole-3-carbonitrile 
• 1603826-53-4 6-(tert-butyl)-4-phenyl-6H-pyrazolo[3,4-c]isothiazole-3-carbonitrile 
• 817641-87-5 1-tert-butyl-3-cyclobutyl-4-methyl-1,7-dihydro-pyrazolo[3,4-b]pyridin-6-one 
• 442850-80-8 N-(2-tert-butyl-5-phenyl-2H-pyrazol-3-yl)-thiobenzamide 
• 442850-83-1 N-(5-phenyl-2H-pyrazol-3-yl)-thiobenzamide 
• 442850-74-0 N-(2-tert-butyl-5-phenyl-2H-pyrazol-3-yl)-benzamide 

Relevant articles and documents

HSP90 INHIBITORS AND USES THEREOF

Herein is described the design and synthesis of resorcylate aminopyrazole compounds. These compounds show broad, potent and fungal-selective Hsp90 inhibitory activity. These compounds also find use in treating Hsp90 related deseases.

Gas-phase synthesis of pyrazolo[3,4- b ]pyridin-4-ones

Flash vacuum pyrolysis (FVP) at 500-600 °C of 1-substituted pyrazolylaminomethylene derivatives of Meldrum's acid provides 1-substituted pyrazolo[3,4-b]pyridin-4-ones in high yields. If the 1-substituent is a tert-butyl group, FVP at 750-850 °C causes elimination of 2-methyl-1-propene to give the parent pyrazolo[3,4-b]pyridin-4-one.

PYRAZOLO`3,4-B!PYRIDIN-6-ONES AS GSK-3 INHIBITORS

The invention provides compounds of formula (I), the stereoisomers and prodrugs thereof, and the pharmaceutically acceptable salts of the compounds, stereoisomers, and prodrugs, wherein R1, R2, and R3 are as defined herein; pharmaceutical compositions thereof; and use thereof in the treatment of, inter alia, conditions, diseases, and symptoms such as diabetes, dementia, Alzheimer's Disease, stroke, schizophrenia, depression, hair loss, and cancer.