442852-06-4

Basic information

• Product Name: N-octyl-N-trifluoroacetyl-2,3,6-tri-O-benzoyl-5a-carba-β-D-xylo-hex-5(5a)-enopyranosylamine
• Synonyms: N-octyl-N-trifluoroacetyl-2,3,6-tri-O-benzoyl-5a-carba-β-D-xylo-hex-5(5a)-enopyranosylamine
• CAS NO: 442852-06-4
• Molecular Weight: 695.733
• Mol File: 442852-06-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-octyl-N-trifluoroacetyl-2,3,6-tri-O-benzoyl-5a-carba-β-D-xylo-hex-5(5a)-enopyranosylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-octyl-N-trifluoroacetyl-2,3,6-tri-O-benzoyl-5a-carba-β-D-xylo-hex-5(5a)-enopyranosylamine(442852-06-4)
• EPA Substance Registry System: N-octyl-N-trifluoroacetyl-2,3,6-tri-O-benzoyl-5a-carba-β-D-xylo-hex-5(5a)-enopyranosylamine(442852-06-4)

Safety Data

• Hazardous Substances Data: 442852-06-4(Hazardous Substances Data)

Upstream product

• 177898-40-7 N-octyl-2,3:4,6-di-O-isopropylidene-5a-carba-β-D-xylo-hex-5(5a)-enopyranosylamine 
• 442852-04-2 N-octyl-N-trifluoroacetyl-4,6-O-benzylidene-5a-carba-β-D-xylo-hex-5(5a)-enopyranosylamine 
• 442851-94-7 N-octyl-N-trifluoroacetyl-2,3:4,6-di-O-isopropylidene-5a-carba-β-D-xylo-hex-5(5a)-enopyranosylamine 
• 98-88-4 benzoyl chloride 

Downstream Products

• 442852-07-5 N-octyl-N-trifluoroacetyl-4-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-2,3,6-tri-O-benzoyl-5a-carba-β-D-xylo-hex-5(5a)-enopyranosylamine 

Relevant articles and documents

Chemical modification of the beta-glucocerebrosidase inhibitor N-octyl-beta-valienamine: synthesis and biological evaluation of 4-epimeric and 4-O-(beta-D-galactopyranosyl) derivatives.

N-Octyl-beta-valienemine (1), a potent beta-glucocerebrosidase inhibitor, was chemically transformed into two biologically interesting compounds: the 4-epimer, beta-galacto-type N-octyl-valienamine, and the 4-O-(beta-D-galactopyranosyl) derivative, a carba-lactosylceramide analogue. The former, interestingly, could be demonstrated to act as a very effective inhibitor (IC(50)=0.3 microM) of human beta-galactosidase. The latter exhibited moderate inhibitory activity (IC(50)=20 microM) against beta-glucocerebrosidase (mouse liver).