4433-78-7 Usage
General Description
N-[4-(acetylamino)phenyl]-3-oxobutyramide, also known as N-Acetyl-4-aminophenyl Butyramide, is a chemical compound with a molecular formula C13H14N2O3. It is an amide derivative of 4-aminophenyl butyrate and contains an acetyl group attached to the amino group of the phenyl ring. N-[4-(acetylamino)phenyl]-3-oxobutyramide is commonly used in the synthesis of pharmaceuticals and organic compounds and has potential applications in the field of medicinal chemistry. It has been studied for its potential anti-inflammatory and analgesic properties, and its structure and properties make it a valuable intermediate in the production of various bioactive molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 4433-78-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,4,3 and 3 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 4433-78:
(6*4)+(5*4)+(4*3)+(3*3)+(2*7)+(1*8)=87
87 % 10 = 7
So 4433-78-7 is a valid CAS Registry Number.
InChI:InChI=1/C12H14N2O3/c1-8(15)7-12(17)14-11-5-3-10(4-6-11)13-9(2)16/h3-6H,7H2,1-2H3,(H,13,16)(H,14,17)
4433-78-7Relevant articles and documents
HFIP-mediated strategy towards β-oxo amides and subsequent Friedel-Craft type cyclization to 2?quinolinones using recyclable catalyst
Kabi, Arup K.,Gujjarappa, Raghuram,Vodnala, Nagaraju,Kaldhi, Dhananjaya,Tyagi, Ujjawal,Mukherjee, Kalisadhan,Malakar, Chandi C.
supporting information, (2020/10/20)
A simple and cost-effective 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP)-mediated protocol for the synthesis of β-oxo amides has been described by using amines and β-keto esters as substrates. The reaction conditions were found to be highly efficient towards the cleavage of C[sbnd]O bond and consequent formation of the products in excellent yields and selectivity. The obtained β-oxo amides were further transformed in to the synthetically useful 2?quinolinones via intramolecular Friedel-Craft type cyclization of aromatic ring using ferrites as a recyclable catalyst. A spectrum of substrates bearing broad range of functional groups were well tolerated under the reaction conditions. The proposed mechanistic pathways were substantially verified by literature and mass-spectroscopic evidences.
