444643-04-3Relevant articles and documents
Highly diastereoselective hydrogenation of imines by a bimetallic Pd-Cu heterogeneous catalyst
Mueslehiddinoglu, Jale,Li, Jun,Tummala, Srinivas,Deshpande, Rajendra
experimental part, p. 890 - 894 (2011/03/20)
An efficient and practical heterogeneous bimetallic Pd-Cu/C catalyst was identified as an alternative to Raney nickel for the highly diastereoselective hydrogenation of imines prepared from prochiral ketones and α- phenylethylamines. Chiral amines were ob
Highly regioselective hydrogenolysis of bis(α-methylbenzyl)amine derivatives affected by the trifluoromethyl substituent on the aromatic ring
Kanai, Masatomi,Yasumoto, Manabu,Kuriyama, Yokusu,Inomiya, Kenjin,Katsuhara, Yutaka,Higashiyama, Kimio,Ishii, Akihiro
, p. 1007 - 1010 (2007/10/03)
(Matrix presented) The highly regioselective hydrogenolysis of bis(α-methylbenzyl)amine derivatives proceeded with influence not from the electronic effect but from the steric effect of the trifluoromethyl substituent on the aromatic ring to provide a practical asymmetric synthesis of trifluoromethyl-substituted α-phenylethylamines.