444680-80-2Relevant articles and documents
Asymmetric total synthesis of 11-deoxytetrodotoxin,a naturally occurring congener
Nishikawa, Toshio,Asai, Masanori,Isobe, Minoru
, p. 7847 - 7852 (2007/10/03)
Tetrodotoxin, a toxic principle of puffer fish poisoning, is a specific blocker of sodium channel. Despite many synthetic efforts since the structure elucidation in 1964, the only total synthesis of the racemic tetrodotoxin has been reported by Kishi and