445041-75-8 Usage
Description
(2R)-2-[4-[(7-Bromoquinolin-2-yl)oxy]phenoxy]propanoic acid, also known as BR5QP, is a chemical compound with the molecular formula C20H15BrNO4. It is a derivative of quinoline, a heterocyclic aromatic compound, and is commonly used in the field of medicinal chemistry. BR5QP has been studied for its potential therapeutic applications, particularly in the treatment of cancer and inflammatory diseases. It is known to exhibit anti-inflammatory and anticancer properties, making it a promising candidate for the development of new pharmaceutical drugs. (2R)-2-[4-[(7-Bromoquinolin-2-yl)oxy]phenoxy]propanoic acid's structure and properties make it an important target for further research and development in the medical and pharmaceutical fields.
Uses
Used in Pharmaceutical Industry:
BR5QP is used as a pharmaceutical candidate for the development of new drugs due to its anti-inflammatory and anticancer properties. Its potential therapeutic applications make it a promising compound for the treatment of cancer and inflammatory diseases.
Used in Cancer Treatment:
BR5QP is used as an anticancer agent, targeting various types of cancer. Its anti-inflammatory and anticancer properties make it a promising candidate for the development of new cancer treatments.
Used in Inflammatory Disease Treatment:
BR5QP is used as an anti-inflammatory agent, targeting various inflammatory diseases. Its anti-inflammatory properties make it a promising candidate for the development of new treatments for inflammatory conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 445041-75-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,5,0,4 and 1 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 445041-75:
(8*4)+(7*4)+(6*5)+(5*0)+(4*4)+(3*1)+(2*7)+(1*5)=128
128 % 10 = 8
So 445041-75-8 is a valid CAS Registry Number.
445041-75-8Relevant articles and documents
PROCESS FOR THE PREPARATION OF (2R)-2-[4-(7-BROMO-2-QUINOLYLOXY)PHENOXY]PROPANOIC ACID
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Page/Page column 11, (2009/03/07)
Industrially applicable process for preparing (2R)-2-[4-(7-bromo-2-quinolyloxy)phenoxy] propanoic acid, and salts thereof.
II. Synthesis and biological evaluation of some bioisosteres and congeners of the antitumor agent, 2-{4-[(7-chloro-2-quinoxalinyl)oxylphenoxy}propionic acid (XK469)
Hazeldine, Stuart T.,Polin, Lisa,Kushner, Juiwanna,White, Kathryn,Bouregeois, Nicole M.,Crantz, Brianna,Palomino, Eduardo,Corbett, Thomas H.,Horwitz, Jerome P.
, p. 3130 - 3137 (2007/10/03)
XK469 (1) is among the most highly and broadly active antitumor agents to have been evaluated in our laboratories. Subsequent developmental studies led to the entry of (R)-(+) 1 (NSC 698215) into phase 1 clinical trials (NIH UO1-CA62487). The antitumor me
