445303-09-3

Basic information

• Product Name: 4-CHLORO-3-TRIFLUOROMETHYLPHENYLBORONIC ACID, PINACOL ESTER
• Synonyms: 2-[4-Chloro-3-(trifluoromethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, 2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzotrifluoride;2-(4-chloro-3-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;4-CHLORO-3-TRIFLUOROMETHYLPHENYLBORONIC ACID, PINACOL ESTER;4-Chloro-3-trifluoromethylphenylboronic acid,pinacol;1,3,2-Dioxaborolane, 2-[4-chloro-3-(trifluoroMethyl)phenyl]-4,4,5,5-tetraMethyl-
• CAS NO: 445303-09-3
• Molecular Formula: C₁₃H₁₅BClF₃O₂
• Molecular Weight: 306.52
• Product Categories: Aryl;Organoborons;Trifluoromethyl
• Mol File: 445303-09-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 327.076°C at 760 mmHg
• Flash Point: 151.611°C
• Appearance: /
• Density: 1.237g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.471
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-CHLORO-3-TRIFLUOROMETHYLPHENYLBORONIC ACID, PINACOL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLORO-3-TRIFLUOROMETHYLPHENYLBORONIC ACID, PINACOL ESTER(445303-09-3)
• EPA Substance Registry System: 4-CHLORO-3-TRIFLUOROMETHYLPHENYLBORONIC ACID, PINACOL ESTER(445303-09-3)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22
• Hazardous Substances Data: 445303-09-3(Hazardous Substances Data)

Usage

General Description

4-Chloro-3-trifluoromethylphenylboronic acid, pinacol ester is a chemical compound used in organic synthesis as a reagent for cross-coupling reactions with various organic substrates. It is a boronic acid-derived reagent that serves as a source of the phenyltrifluoroborate functional group, which is valuable in pharmaceutical and agrochemical industries. 4-CHLORO-3-TRIFLUOROMETHYLPHENYLBORONIC ACID, PINACOL ESTER is stable and easy to handle, making it a versatile tool for the construction of complex molecular architectures. Its unique combination of reactivity and stability makes it a valuable building block for the synthesis of diverse biologically active compounds.

InChI:InChI=1/C13H15BClF3O2/c1-11(2)12(3,4)20-14(19-11)8-5-6-10(15)9(7-8)13(16,17)18/h5-7H,1-4H3

Upstream product

• 445-01-2 5-bromo-2-chlorobenzotrifluoride 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 1737-36-6 4-chloro-3-(trifluoromethyl)benzoic acid 
• 1007882-60-1 C₁₉H₂₁ClF₃N₃O₂ 
• 1007882-60-1 C₁₉H₂₁ClF₃N₃O₂ 

Relevant articles and documents

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