4495-52-7 Usage
Appearance
Colorless liquid
Odor
Strong ammonia-like
Salt form
Dihydrochloride
Uses
a. Corrosion inhibitor
b. Curing agent in epoxy resin formulations
c. Pharmaceutical applications
d. Starting material for organic compound synthesis
Hazardous properties
a. Skin and eye irritation
b. Harmful if ingested
c. Harmful if inhaled
Handling precautions
Handle with care due to hazardous nature
Check Digit Verification of cas no
The CAS Registry Mumber 4495-52-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,4,9 and 5 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 4495-52:
(6*4)+(5*4)+(4*9)+(3*5)+(2*5)+(1*2)=107
107 % 10 = 7
So 4495-52-7 is a valid CAS Registry Number.
4495-52-7Relevant articles and documents
Ni-Catalyzed Dual C-H Annulation of Benzimidazoles with Alkynes for Synthesis of π-Extended Heteroarenes
Qi, Shao-Long,Li, Yue,Li, Jiang-Fei,Zhang, Tao,Luan, Yu-Xin,Ye, Mengchun
supporting information, p. 4034 - 4039 (2021/05/26)
Transition metal catalyzed dual C-H activation and annulation with alkynes was an attractive protocol to construct polycyclic π-extended structures. However, most of them were dominated by noble metal catalysts. Disclosed herein was the study of base-metal Ni-catalysis for dual C-H annulation of N-aromatic imidazole, which produced a range of desired polycyclic aza-quinolines in 48-95% yields. The use of bifunctional phosphine oxide ligand proved to be critical for success.
