449815-31-0

Basic information

• Product Name: Pentononitrile, 2,3-anhydro-3-C-butyl-4,5-dideoxy-4-methyl- (9CI)
• Synonyms: Pentononitrile, 2,3-anhydro-3-C-butyl-4,5-dideoxy-4-methyl- (9CI)
• CAS NO: 449815-31-0
• Molecular Formula: C10H17NO
• Molecular Weight: 167.24808
• Product Categories: ISOPROPYL
• Mol File: 449815-31-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Pentononitrile, 2,3-anhydro-3-C-butyl-4,5-dideoxy-4-methyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Pentononitrile, 2,3-anhydro-3-C-butyl-4,5-dideoxy-4-methyl- (9CI)(449815-31-0)
• EPA Substance Registry System: Pentononitrile, 2,3-anhydro-3-C-butyl-4,5-dideoxy-4-methyl- (9CI)(449815-31-0)

Safety Data

• Hazardous Substances Data: 449815-31-0(Hazardous Substances Data)

Upstream product

• 13019-20-0 2-methylheptan-3-one 
• 107-14-2 chloroacetonitrile 

Relevant articles and documents

Rearrangement of epoxynitriles: A convenient homologation of acyclic and cyclic ketones to carboxylic acids

A convenient two-step homologation of both aliphatic and aromatic ketones to the corresponding carboxylic acid has been developed. First ketones were converted to epoxynitriles with the Darzens reaction. Second, a Lewis acid mediated rearrangement of these epoxynitriles with lithium bromide was achieved to give homologated secondary alkanoic acids (as well as aryl-alkanoic) in good yields. The mechanism and the scope of the rearrangement reaction were investigated. This strategy constitutes a two- step homologation of ketones to secondary carboxylic acids.