4506-62-1Relevant articles and documents
SAR study of 4-arylazo-3,5-diamino-1: H -pyrazoles: identification of small molecules that induce dispersal of Pseudomonas aeruginosa biofilms
Andersen, Jens B.,Givskov, Michael,Hultqvist, Louise D.,Jakobsen, Tim H.,Jansen, Charlotte U.,Nielsen, Thomas E.,Nilsson, Martin,Qvortrup, Katrine M.,Tolker-Nielsen, Tim,Uhd, Jesper
, p. 1868 - 1878 (2021/12/22)
By screening of a collection of 50 000 small-molecule compounds, we recently identified 4-arylazo-3,5-diamino-1H-pyrazoles as a novel group of anti-biofilm agents. Here, we report a SAR study based on 60 analogues by examining ways in which the pharmacoph
Asymmetric aluminum complex containing o-phenylenediamine group, preparation method and application thereof
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Paragraph 0033, (2018/09/28)
The invention discloses an asymmetric aluminum complex containing o-phenylenediamine group and a preparation method and application thereof, the asymmetric aluminum complex has the structural formulaof formula I, wherein R is hydrogen, C1-C4 alkane or halogen. An asymmetric aluminum complex catalyst containing the o-phenylenediamine group is obtained by reacting a ligand with trimethylaluminum, apreparation method is simple, low in cost and high in product yield, the asymmetric aluminum complex has a special structure, and various structural changes, metal center aluminum can be coordinatedwith divalent N, N, O and O of the ligand, the asymmetric aluminum complex catalyst can be used as a catalyst for ring-opening polymerization of cyclic lactones, has high catalytic activity, good stereoselectivity and fast reaction rate, polymerization operation is simple, the obtained polymerization product has a narrow molecular weight distribution, a controllable molecular weight and a high yield, and the asymmetric aluminum complex catalyst can be widely used for ring-opening polymerization of the cyclic lactones, and is an ideal catalyst.
The aminocarbonylation of 1,2-diiodoarenes with primary and secondary amines catalyzed by palladium complexes with imidazole ligands
Wójcik, Przemys?aw,Trzeciak, Anna M.
, p. 73 - 83 (2018/05/22)
The efficient carbonylative cyclization of 1,2-diiodobenzene with different primary and secondary amines was performed using a palladium complex with an imidazole ligand, PdCl2(BIM)2, as a catalyst. In reactions performed at 1 atm of CO with primary amines, phthalimides were obtained as the only products with yields of up to 100% in 4 h. An even shorter time, 1 h, was sufficient to obtain the same products employing methyl-2-iodobenzoate as a substrate instead of 1,2-diiodobenzene. In an analogous reaction with secondary amines, 1,2-diiodobenzene was converted to three products, formed in amounts dependent on the reaction conditions. The presence of Pd NPs and soluble palladium intermediates indicated their participation in the catalytic reaction.
