4512-31-6

Basic information

• Product Name: Alanine, 2-methyl-N-[(phenylmethoxy)carbonyl]-, 1,1-dimethylethyl ester
• CAS NO: 4512-31-6
• Molecular Formula: C16H23NO4
• Molecular Weight: 293.363
• Mol File: 4512-31-6.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Alanine, 2-methyl-N-[(phenylmethoxy)carbonyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Alanine, 2-methyl-N-[(phenylmethoxy)carbonyl]-, 1,1-dimethylethyl ester(4512-31-6)
• EPA Substance Registry System: Alanine, 2-methyl-N-[(phenylmethoxy)carbonyl]-, 1,1-dimethylethyl ester(4512-31-6)

Safety Data

• Hazardous Substances Data: 4512-31-6(Hazardous Substances Data)

Upstream product

• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 98946-18-0 tert-Butyl 2,2,2-trichloroacetimidate 
• 15030-72-5 Z-Aib-OH 
• 501-53-1 benzyl chloroformate 
• 1907-33-1 lithium tert-butoxide 
• 115-11-7 isobutene 

Downstream Products

• 4512-38-3 Z-(Aib)4-OtBu 
• 1185571-72-5 tert-butyl N-({4-[6-amino-5-(2,4-difluorobenzoyl)-2-oxopyridin-1(2H)-yl]phenyl}acetyl)-2-methylalaninate 
• 1185571-70-3 tert-butyl N-(2-{4-[6-amino-5-(2,4-difluorobenzoyl)-2-oxopyridin-1(2H)-yl]phenyl}ethyl)-2-methylalaninate 
• 1361051-51-5 Z-Sar-Aib-O(t-Bu) 
• 845877-33-0 Z-Aib-Gly-Leu-Aib-Ot-Bu 
• 1359857-17-2 Fmoc-Aib-Lys(Z)-Leu-Aib-OtBu 
• 1359857-15-0 Z-Gly-Gly-Leu-Aib-OtBu 
• 845877-32-9 Z-Gly-Leu-Aib-Ot-Bu 
• 669766-81-8 C₂₂H₃₄N₂O₅ 
• 1359857-28-5 Z-Aib-Gly-Leu-Aib-Gly-Gly-Leu-Aib-OtBu 
• 83537-96-6 Benzyloxycarbonyl-L-prolyl-leucyl-α-aminoisobutyryl-α-aminoisobutyric acid tert-butyl ester 
• 84758-65-6 Z-L-Gln-Aib-OtBu 
• 84758-64-5 Z-L-Val-Aib-OtBu 
• 84758-84-9 Z-Ala-Aib-OtBu 

Relevant articles and documents

Deracemization and the first CD spectrum of a 310-helical peptide made of achiral α-amino-isobutyric acid residues in a chiral membrane mimetic environment

Interaction of the racemic helical homo-octapeptide made by the achiral Cα-methyl alanine (Aib) amino acid with a chiral enantiopure micellar aggregate made of N-dodecylproline led to the deracemization of the helical Aib sequence thus allowing

Rational design of gold(III)-dithiocarbamato peptidomimetics for the targeted anticancer chemotherapy

As a further extension of our research work focusing on the development of gold(III)-dithiocarbamato dtc derivatives of oligopeptides as potential anticancer agents, complexes [AuIIIX2(dtc-Sar-l-Ser(t-Bu)- O(t-Bu))] (X = Br (1a)/Cl (

ENZYME AND RECEPTOR MODULATION

Covalent conjugates of an α,α-disubstituted glycine ester and a modulator of the activity of a target intracellular enzyme or receptor, wherein the ester group of the conjugate is hydrolysable by one or more intracellular carboxylesterase enzymes to the corresponding acid and the α,α-disubstituted glycine ester is conjugated to the modulator at a position remote from the binding interface between the inhibitor and the target enzyme or receptor pass into cells and the active acid hydrolysis product accumulates within the cells.