4519-46-4 Usage
Description
METHYL ALPHA-BROMOACRYLATE 95 is a chemical compound that is known for its ability to undergo various chemical reactions and transformations. It is a versatile molecule that can be used in the synthesis of different compounds and materials due to its reactivity and functional groups.
Uses
Used in Polymer Synthesis:
METHYL ALPHA-BROMOACRYLATE 95 is used as a monomer in the polymer industry for the production of copolymers. It undergoes radical copolymerization with vinyl triacetoxysilane (VTAS) in the presence of azobisisobutyronitrile as the initiator, resulting in copolymers with unique properties.
Used in Organic Synthesis:
In the field of organic synthesis, METHYL ALPHA-BROMOACRYLATE 95 is used as a starting material for the synthesis of various compounds. One example is the dibromocyclopropanation reaction, which yields methyl 1,1,2-tribromocyclopropanecarboxylate. METHYL ALPHA-BROMOACRYLATE 95 can be further reduced with zinc dust and deuterium oxide to synthesize methyl acrylate-α-d with high isotopic purity.
Used in Ester Enolate Formation:
METHYL ALPHA-BROMOACRYLATE 95 is also used in the formation of ester enolates, which are important intermediates in organic chemistry. These ester enolates can be obtained through conjugate addition reactions with various nucleophiles such as methoxide, thiolates, oxime anions, hydrazones, and EtZnCl. The resulting ester enolates can be used in various synthetic transformations and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 4519-46-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,5,1 and 9 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 4519-46:
(6*4)+(5*5)+(4*1)+(3*9)+(2*4)+(1*6)=94
94 % 10 = 4
So 4519-46-4 is a valid CAS Registry Number.
InChI:InChI=1/C5H7BrO2/c1-3-8-5(7)4(2)6/h2-3H2,1H3
4519-46-4Relevant articles and documents
Α, α-difluoropropionic production of esters
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Paragraph 0140-0142, (2016/10/10)
PROBLEM TO BE SOLVED: To provide a practical method of producing α,α-difluoro esters important as pharmaceutical and agricultural chemical intermediates. SOLUTION: The α,α-difluoro esters are produced by reacting α-halogeno-α-fluoro esters with salts or complexes comprising an organic base and hydrogen fluoride. Dehydrohalogenation of side reaction is controlled in the production method. Only α-fluoro-α,β-unsaturated esters of by-products are treated to be brought specifically into a high boiling-point, a boiling point difference gets remarkably large thereby between the α,α-difluoro ester of an objective product and the unsaturated ester of by-product, and a high purity product of the objective product is efficiently obtained by fractional distillation of a simple operation. The method is the practical method of producing the α,α-difluoro esters capable of solving a problem point in a prior technique. COPYRIGHT: (C)2012,JPOandINPIT
ISOMERIZATION OF 5-ACYL-6-HALO-1,6-DIAZABICYCLOHEXANES, A CASE OF INVERSION RATHER THAN 1,2-ACYL MIGRATION
Shustov, G. V.,Denisenko, S. N.,Chervin, I. I.,Zolotoi, A. B.,D'yachenko, O. A.,et all
, p. 1076 - 1079 (2007/10/02)
X-ray diffraction structural analysis and 13 C and 15 N NMR spectroscopy were used to establish that the final product of the halogenation of 5-acyl-1,6-diazabicyclohexane is the oxo-6-halo derivative.Thus, the observed transformation of the initially formed endo-N-chloro isomer is an inversion and not 1,2-acyl migration as previously proposed.
