452056-98-3

Basic information

• Product Name: 2-Pyridinamine, 4-[4-(4-fluorophenyl)-1-methyl-2-(methylthio)-1H-imidazol-5-yl]-
• CAS NO: 452056-98-3
• Molecular Formula: C16H15FN4S
• Molecular Weight: 314.386
• Mol File: 452056-98-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-Pyridinamine, 4-[4-(4-fluorophenyl)-1-methyl-2-(methylthio)-1H-imidazol-5-yl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinamine, 4-[4-(4-fluorophenyl)-1-methyl-2-(methylthio)-1H-imidazol-5-yl]-(452056-98-3)
• EPA Substance Registry System: 2-Pyridinamine, 4-[4-(4-fluorophenyl)-1-methyl-2-(methylthio)-1H-imidazol-5-yl]-(452056-98-3)

Safety Data

• Hazardous Substances Data: 452056-98-3(Hazardous Substances Data)

Upstream product

• 549505-57-9 N-{4-[2-cyano-2-(4-fluoro-phenyl)-1-hydroxy-vinyl]-pyridin-2-yl}-acetamide 
• 452056-82-5 N-{4-[2-(4-fluorophenyl)-2-hydroxyliminoacetyl]pyridin-2-yl}acetamide 
• 452056-81-4 N-{4-[2-(4-fluorophenyl)acetyl]pyridin-2-yl}acetamide 
• 452056-80-3 1-(2-aminopyridin-4-yl)-2-(4-fluorophenyl)ethanone 
• 452056-88-1 N-{4-[4-(4-fluorophenyl)-1-methyl-2-thioxo-2,3-dihydro-1H-imidazol-5-yl]pyridin-2-yl}acetamide 
• 452056-83-6 N-{4-[5-(4-fluorophenyl)-1-oxy-3-methyl-3H-imidazol-4-yl]pyridin-2-yl}acetamide 
• 695-34-1 2-Amino-4-methylpyridine 
• 452056-93-8 N-{4-[4-(4-fluorophenyl)-1-methyl-2-methylsulfanyl-1H-imidazol-5-yl]pyridin-2-yl}acetamide 

Downstream Products

• 452057-00-0 N-(4-(4-(4-fluorophenyl)-1-methyl-2-(methylthio)-1H-imidazol-5-yl)pyridin-2-yl)cyclopropanecarboxamide 

Relevant articles and documents

Tri- and tetrasubstituted imidazoles as p38α mitogen-activated protein kinase inhibitors

The synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles as potent p38α mitogen-activated protein kinase inhibitors is described. The trisubstituted imidazole series was found to be more potent than the tetrasubstituted imidazole seri

2-SULFINYL- AND 2-SULFONYL-SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR USE AS CYTOKINE INHIBITORS

The invention relates to 2-sulfinyl- or 2-sulfonyl-substituted imidazole derivatives of the formula (I) in which the radicals R1, R2, R3 and R4 have the meaning indicated in the description. The compounds of the