452962-66-2Relevant articles and documents
Novel 1,4-palladium migration in organopalladium intermediates derived from o-lodobiaryls
Campo, Marino A.,Larock, Richard C.
, p. 14326 - 14327 (2002)
A novel 1,4-palladium migration in organopalladium intermediates derived from o-iodobiaryls has been observed under modified Heck reaction conditions. This migration process can be switched "on" or "off" by simply choosing the appropriate reaction conditi
Synthesis of fluoren-9-ones by the palladium-catalyzed cyclocarbonylation of o-halobiaryls
Campo, Marino A.,Larock, Richard C.
, p. 5616 - 5620 (2007/10/03)
The synthesis of various substituted fluoren-9-ones has been accomplished by the palladium-catalyzed cyclocarbonylation of o-halobiaryls. The cyclocarbonylation of 4′-substituted 2-iodobiphenyls produces very high yields of 2-substituted fluoren-9-ones bearing either electron-donating or electron-withdrawing substituents. 3′-Substituted 2-iodobiphenyls afford 3-substituted fluoren-9-ones in excellent yields with good regioselectivity. This chemistry has been successfully extended to polycyclic fluorenones and fluorenones containing fused isoquinoline, indole, pyrrole, thiophene, benzothiophene, and benzofuran rings.
