453518-18-8

Basic information

• Product Name: 1-(5-benzyloxy-2-nitrophenol)-2-propen-1-one
• Synonyms: 1-(5-benzyloxy-2-nitrophenol)-2-propen-1-one
• CAS NO: 453518-18-8
• Molecular Weight: 283.284
• Mol File: 453518-18-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(5-benzyloxy-2-nitrophenol)-2-propen-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(5-benzyloxy-2-nitrophenol)-2-propen-1-one(453518-18-8)
• EPA Substance Registry System: 1-(5-benzyloxy-2-nitrophenol)-2-propen-1-one(453518-18-8)

Safety Data

• Hazardous Substances Data: 453518-18-8(Hazardous Substances Data)

Upstream product

• 453518-17-7 1-(5-benzyloxy-2-nitrophenol)-2-propen-1-ol 

Downstream Products

• 35364-15-9 2'-amino-5'-hydroxypropiophenone 
• 453518-19-9 1-(5-hydroxy-2-nitrophenyl)propan-1-one 

Relevant articles and documents

METHOD OF SYNTHESIZING CAMPTOTHECIN-RELATING COMPOUNDS

The present invention is to prepare efficiently 2'-amino-5'-hydroxypropiophenone corresponding to the AB-ring part of camptothecin (CPT) skeleton and a tricyclic ketone corresponding to the CDE-ring part in order to provide efficiently CPT by the total synthesis, which is a starting material for irinotecan hydrochloride and various kinds of camptothecin derivatives, and to provide stably CPT and its derivatives.