4537-09-1Relevant articles and documents
An ether-linked halogenated phenazine-quinone prodrug model for antibacterial applications
Huigens, Robert W.,Jin, Shouguang,Kim, Young S.,Liu, Ke,Yang, Hongfen
supporting information, p. 6603 - 6608 (2021/08/12)
Antibiotic-resistant infections present significant challenges to patients. As a result, there is considerable need for new antibacterial therapies that eradicate pathogenic bacteria through non-conventional mechanisms. Our group has identified a series o
Preparation method of trimethylhydroquinone
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Paragraph 0039; 0049; 0047; 0048; 0055; 0056; 0063; 0064, (2019/01/07)
The invention discloses a preparation method of trimethylhydroquinone. The preparation method is characterized in that isophorone is used as an initial raw material and oxidized into oxoisophorone, then an acylation reaction occurs in the oxoisophorone and an acylating agent to produce trimethyl hydroquinone diester, and the trimethyl hydroquinone diester is hydrolyzed to produce 2,3,5-trimethylhydroquinone. The method disclosed by the invention has cheap and easily-available raw materials and simple syntheses steps, a used solvent is easy to recover and reuse, and the method needs not use ofa big amount of acid and alkali, thereby reducing pollution of the environment, being convenient for large-scale industrial production and having good application prospects.
Catalytic Asymmetric Cycloadditions of Silyl Nitronates Bearing α-Aryl Group
Jiang, Minghui,Feng, Lifei,Feng, Juanjuan,Jiao, Peng
supporting information, p. 2210 - 2213 (2017/05/12)
1,3-Dipolar cycloadditions of 2-alkylacroleins or atropaldehyde with triisopropylsilyl nitronates bearing an α-aryl group produced 3-aryl-2-isoxazolines having a chiral quaternary center in up to 94% ee and up to 88% yield with the aid of Corey’s oxazaborolidine catalyst. Specifically, the TIPS nitronate with an α-(p-methoxyphenyl) group gave mainly the 2-isoxazolines having an all-carbon quaternary center.