4545-85-1

Basic information

• Product Name: Benzyldichlorophosphine
• Synonyms: Benzyldichlorophosphine
• CAS NO: 4545-85-1
• Molecular Formula: C₇H₇Cl₂P
• Molecular Weight: 193.01
• Mol File: 4545-85-1.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 110-111 °C(Press: 12 Torr)
• Appearance: /
• Density: 1.300 g/cm3
• CAS DataBase Reference: Benzyldichlorophosphine(CAS DataBase Reference)
• NIST Chemistry Reference: Benzyldichlorophosphine(4545-85-1)
• EPA Substance Registry System: Benzyldichlorophosphine(4545-85-1)

Safety Data

• Hazardous Substances Data: 4545-85-1(Hazardous Substances Data)

Upstream product

• 14990-01-3 benzylphosphine 
• 100-39-0 benzyl bromide 
• 74483-17-3 chlorophosphane 
• 76684-21-4 Phenylmethylidynephosphine 
• 1080-32-6 O,O-diethyl benzylphosphonate 
• 76684-22-5 C₇H₆ClP 
• 1589-82-8 phenylmagnesium bromide 
• 100-44-7 benzyl chloride 
• 780-24-5 dibenzylmercury(II) 

Downstream Products

• 13954-37-5 Benzyldimethylphosphin 
• 120011-49-6 benzyl-di(2-methoxyphenyl)phosphine 
• 1466553-15-0 P-benzyldithieno[3,2-b:2',3'-d]phosphole 4-sulfide 
• 1466553-16-1 P,P-dibenzyldithieno[3,2-b:2',3'-d]phospholium bromide 
• 1466553-17-2 P-benzyl-2,6-bis(t-butyldimethylsilyl)dithieno[3,2-b:2',3'-d]phosphole 
• 1466553-13-8 P-benzyldithieno[3,2-b:2',3'-d]phosphole 
• 143331-50-4 Benzyl-phosphonic acid bis-[(2R,3S,5R)-3-(tert-butyl-dimethyl-silanyloxy)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl] ester 
• 143331-47-9 Benzyl-phosphonic acid bis-[(2R,3S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-trityloxymethyl-tetrahydro-furan-3-yl] ester 
• 120011-50-9 C₂₃H₂₇N₂P 
• 76684-22-5 C₇H₆ClP 
• 141868-67-9 Benzyl-bis-(3-fluoro-phenyl)-phosphane 
• 120011-48-5 Benzyl-bis-(4-trimethylsilanyl-phenyl)-phosphane 
• 85363-47-9 (2Z,4Z,6Z)-9-Benzyl-9-phospha-bicyclo[6.1.0]nona-2,4,6-triene 
• 141868-68-0 Benzyl-bis-(4-fluoro-phenyl)-phosphane 

Relevant articles and documents

Hydrogen/Halogen Exchange of Phosphines for the Rapid Formation of Cyclopolyphosphines

The hydrogen/halogen exchange of phosphines has been exploited to establish a truly useable substrate scope and straightforward methodology for the formation of cyclopolyphosphines. Starting from a single dichlorophosphine, a sacrificial proton "donor phosphine"makes the rapid, mild synthesis of cyclopolyphosphines possible: reactions are complete within 10 min at room temperature. Novel (aryl)cyclopentaphosphines (ArP)5 have been formed in good conversion, with the crystal structures presented. The use of catalytic quantities of iron(III) acetylacetonate provides significant improvements in conversion in the context of diphosphine (Ar2P)2 and alkyl-substituted cyclotetra- or cyclopentaphosphine ((AlkylP)n, where n = 4 or 5) formation. Both iron-free and iron-mediated reactions show high levels of selectivity for one specific ring size. Finally, investigations into the reactivity of Fe(acac)3 suggest that the iron species is acting as a sink for the hydrochloric acid byproduct of the reaction.

5,16-Dialkyl(diaryl)-5,16-dihydro-5,16-diphospha-tetraepoxy[22]annulene (2.1.2.1)

Several 5,16-dialkyl(diaryl)-5,16-dihydro-5,16-diphospha-tetraepoxy[22]annulenes (2.1.2.1) 9 as possible precursors of aromatic 5,16-diphospha-tetraepoxy[22]annulenes(2.1.2.1) 8 are synthesized by cyclizing Wittig-reactions of the phosphane dialdehydes 15 with the bis-ylids of the phosphane-bisphosphoniumsalts 19.

Phenylalkyl backbone modified oligodeoxynucleotides, their synthesis and the influence of the alkyl chain length

Phenylalkyl modified phosphoramidites (alkyl chain length n = 1, 2, 3, 5; Fig. 1) were synthesised and incorporated into a DNA hexamer (5′-d(GCCp-GCG); p = place of modification). The obtained diastereomeres were separated by RP-HPLC. After hybridisation