4553-59-7

Basic information

• Product Name: PHENYL-PHENYLAMINO-ACETONITRILE
• Synonyms: PHENYL-PHENYLAMINO-ACETONITRILE;anilino(phenyl)acetonitrile;2-(Phenylamino)-2-phenylacetonitrile;2-Anilino-2-phenylacetonitrile;N,2-Diphenylglycinonitrile;α-(Phenylamino)benzeneacetonitrile;α-Anilinobenzeneacetonitrile;2-phenyl-2-(phenylaMino)acetonitrile
• CAS NO: 4553-59-7
• Molecular Formula: C₁₄H₁₂N₂
• Molecular Weight: 208.26
• Mol File: 4553-59-7.mol
• Article Data: 178

Chemical Properties

• Boiling Point: 369.7°Cat760mmHg
• Flash Point: 177.4°C
• Appearance: /
• Density: 1.155g/cm³
• Vapor Pressure: 1.17E-05mmHg at 25°C
• Refractive Index: 1.639
• CAS DataBase Reference: PHENYL-PHENYLAMINO-ACETONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: PHENYL-PHENYLAMINO-ACETONITRILE(4553-59-7)
• EPA Substance Registry System: PHENYL-PHENYLAMINO-ACETONITRILE(4553-59-7)

Safety Data

• Hazard Codes: T
• Hazardous Substances Data: 4553-59-7(Hazardous Substances Data)

Usage

General Description

PHENYL-PHENYLAMINO-ACETONITRILE, also known as 2-phenylbenzylamine or benzylphenylamine, is a chemical compound with the molecular formula C14H12N2. It is a white solid that is commonly used in the synthesis of pharmaceuticals and organic compounds. PHENYL-PHENYLAMINO-ACETONITRILE is a derivative of acetophenone with a phenylamino group attached to the acetonitrile moiety. It is often used as a building block in organic synthesis for the preparation of various compounds, including pharmaceuticals, agrochemicals, and dyes. Additionally, it is also utilized in the production of rubber chemicals and as an intermediate in the manufacture of other organic compounds.

InChI:InChI=1/C14H12N2/c15-11-14(12-7-3-1-4-8-12)16-13-9-5-2-6-10-13/h1-10,14,16H

Upstream product

• 7677-24-9 trimethylsilyl cyanide 
• 100-52-7 benzaldehyde 
• 98-95-3 nitrobenzene 
• 538-51-2 benzylidene phenylamine 
• 623-49-4 ethyl cyanoformate 
• 557-21-1 zinc(II) cyanide 
• 62-53-3 aniline 
• 78-67-1 2,2'-azobis(isobutyronitrile) 
• 758640-21-0 N-Benzylaniline 
• 2700-22-3 Benzylidenemalononitrile 
• 773837-37-9 sodium cyanide 
• 108-88-3 toluene 
• 100-51-6 benzyl alcohol 
• 1600-49-3 (isocyanomethanetriyl)tribenzene 

Downstream Products

• 51444-33-8 anilino-phenyl-thioacetic acid amide 
• 60561-61-7 α-anilino-α-phenylacetamide 
• 42164-54-5 N-(2-amino-1-phenylethyl)benzenamine 
• 74-90-8 hydrogen cyanide 
• 2879-66-5 N,N',1,2-tetraphenylethylenediamine 
• 538-51-2 benzylidene phenylamine 
• 62-53-3 aniline 
• 86712-42-7 2,3-dianilino-2,3-diphenyl-propionitrile 
• 861384-66-9 5-cyano-4-methyl-2-oxo-1,5-diphenyl-pyrrolidine-3-carboxylic acid 
• 52240-29-6 (1-methyl-2-oxo-2-phenyl-ethyl)-malonic acid 

Relevant articles and documents

Use of polyazaheterocycles in the assembly of new cadmium sulfate frameworks: Synthesis, structure, and properties

The reaction of cadmium sulfate in the presence of polyazaheterocyclic organic molecules gave rise to a variety of new cadmium sulfate phases in water containing solvothermal reaction. The compounds have two- (I) and three-dimensionally (II-VI) extended s

Aliphatic amine mediated assembly of [M6(mna)6] (M = Cu/Ag) into extended two-dimensional structures: synthesis, structure and Lewis acid catalytic studies

Two new two-dimensional layered compounds, [{Ag6(2-mna)6Cd(Hen)2}{Cd(en)22H2O}(H2O)8],I, and [{M6(2-mna)6Cd(Hen)2}(H2en)(H2

Synthesis and characterization of Pd supported on methane diamine (propyl silane) functionalized Fe3O4 nanoparticles as a magnetic catalyst for synthesis of α-aminonitriles and 2-methoxy-2-phenylacetonitrile derivative via Strecker-t

Pd supported on methane diamine (propyl silane) functionalized Fe3O4 magnetic nanoparticles as an organic–inorganic hybrid heterogeneous catalyst was fabricated and characterized by FT-IR, XRD, SEM, TEM, TGA, VSM, EDX, and ICP-AES te

Electrochemically promoted oxidative α-cyanation of tertiary and secondary amines using cheap AIBN

The electrochemical α-cyanation of tertiary and secondary amines has been developed by using a cheap cyanide reagent, azobisisobutyronitrile (AIBN). The CN radical, generated throughn-Bu4NBr-meidated electrochemical oxidation, participates in a novel α-cyanation reaction under exogenous oxidant-free conditions.

Nano cobalt-copper ferrite catalyzed regioselective α-C(sp3)–H cyanation of amines: Secondary, tertiary, and drug molecules

Oxidative cyanation of sp3C–H bonds at the α position of amines was achieved using CoCuFe2O4 as a catalyst and NaCN as an inexpensive cyanide source at room temperature. CoCuFe2O4 was found to be an active catalyst for Csp [3]-Csp coupling, efficiently delivering valuable α-aminonitriles from tertiary/secondary amines in good yields. The corresponding products were obtained with high selectivity toward α position. In addition, functional group tolerance offered the opportunity for application in late-stage functionalization of biologically active molecules. This transformation proceeds convenient on a gram-scale, and the catalyst can be reused for several runs with consistent catalytic activity.