456-12-2

Basic information

• Product Name: Aegelin
• Synonyms: Aegelin;N-CinnaMoyl-β-hydroxy-4-Methoxyphenyl-aethylaMin;N-(2-Hydroxy-2-(4-Methoxyphenyl)ethyl)cinnaMaMide;Aegeline;Aegeline,N-[2-hydroxy-2(4-Methoxyphenyl) ethyl]-3-phenyl-2-propenaMide
• CAS NO: 456-12-2
• Molecular Formula: C₁₈H₁₉NO₃
• Molecular Weight: 297.34836
• EINECS: 1533716-785-6
• Mol File: 456-12-2.mol
• Article Data: 3

Chemical Properties

• Melting Point: 178-179℃
• Boiling Point: 567.652 °C at 760 mmHg
• Flash Point: 297.105 °C
• Appearance: /
• Density: 1.178 g/cm³
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: Aegelin(CAS DataBase Reference)
• NIST Chemistry Reference: Aegelin(456-12-2)
• EPA Substance Registry System: Aegelin(456-12-2)

Safety Data

• Hazardous Substances Data: 456-12-2(Hazardous Substances Data)

Usage

Description

Aegelin is a bioactive compound that can be extracted from Aegle marmelos leaves, a tree native to India. It possesses various pharmacological properties, including antimicrobial and anti-obesity effects.

Uses

Used in Pharmaceutical Industry:
Aegelin is used as an antimicrobial agent for its effectiveness against 21 types of bacteria, making it a potential candidate for the development of new antibiotics.
Used in Weight Management:
Aegelin is used as an anti-obesity agent due to its ability to promote weight loss and improve metabolic health, offering a natural alternative for obesity treatment and management.

Upstream product

• 56766-24-6 2-hydroxy-2-(4-methoxyphenyl)ethylammonium chloride 
• 102-92-1 Cinnamoyl chloride 
• 66985-48-6 2-(4-methoxyphenyl)-2-(trimethylsilyloxy)acetonitrile 
• 123-11-5 4-methoxy-benzaldehyde 
• 1122469-32-2 (+)-(5S)-2-(trans-styryl)-5-(4-methoxyphenyl)-Δ2-oxazoline 
• 95218-94-3 N-(2-(4-methoxyphenyl)-2-oxoethyl)cinnamamide 

Downstream Products

• 6800-21-1 3-phenyl-propionic acid-(4-methoxy-phenacylamide) 
• 3347-19-1 N-[2-(4-methoxyphenyl)-2-keto-ethyl]-cinnamamide 
• 6821-73-4 3-phenyl-propionic acid-(β-hydroxy-4-methoxy-phenethylamide) 

Relevant articles and documents

Compositions and Methods for Affecting Mental State and Body Composition

The invention discloses compositions, including nutritional products and dietary supplements, comprising aegeline, which is a compound that occurs naturally in the Bael plant. The invention also describes methods comprising the administration of aegeline to mammals. The methods result in increased mental stamina, focus, and energy level, improved mood, increased thermogenesis, increased libido, and anabolic effects and increased strength output and/or muscle mass. These effects can improve cognition, influence body composition, promote weight loss, and/or promote fitness and well-being. A novel method for the synthesis of aegeline is also provided.

SYNTHESES OF NATURAL HYDROXYAMIDES USING TRIMETHYLSILYL CYANIDE

New syntheses of tembamide (1), aegeline (2), and other hydroxyamides, using trimethylsilyl cyanide, are described.