4568-71-2 Usage
Description
3-Benzyl-5-(2-hydroxyethyl)-4-methylthiazolium chloride is an organic compound that serves as a versatile catalyst in various chemical reactions. It is characterized by its ability to facilitate the acyloin condensation of aliphatic aldehydes in the presence of a mild base, as well as the addition of aliphatic and heterocyclic aldehydes to α,β-unsaturated ketones, nitriles, and esters.
Uses
Used in Organic Synthesis:
3-Benzyl-5-(2-hydroxyethyl)-4-methylthiazolium chloride is used as a catalyst for the acyloin condensation of aliphatic aldehydes, enabling the formation of various organic compounds. This reaction is crucial in the synthesis of complex organic molecules and contributes to the development of new pharmaceuticals and other chemical products.
Used in the Addition of Aldehydes to Unsaturated Compounds:
In the chemical industry, 3-Benzyl-5-(2-hydroxyethyl)-4-methylthiazolium chloride is used as a catalyst for the addition of aliphatic and heterocyclic aldehydes to α,β-unsaturated ketones, nitriles, and esters. This process is essential for the synthesis of various chemical intermediates and final products, which can be utilized in different applications, such as pharmaceuticals, agrochemicals, and materials science.
Overall, 3-Benzyl-5-(2-hydroxyethyl)-4-methylthiazolium chloride plays a significant role in the field of organic chemistry, acting as a catalyst to facilitate various reactions and contribute to the synthesis of a wide range of chemical compounds.
Purification Methods
Purify the chloride by recrystallisation from EtOH or H2O. If placed in a bath at 125o and heated at 2o/minute, the melting point is 140.5-141.4o. [Livermore & Sealock J Biol Chem 167 699 1947, Maier & Metzler J Am Chem Soc 79 4386 1957, Beilstein 27 III/IV 1758.]
Check Digit Verification of cas no
The CAS Registry Mumber 4568-71-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,5,6 and 8 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 4568-71:
(6*4)+(5*5)+(4*6)+(3*8)+(2*7)+(1*1)=112
112 % 10 = 2
So 4568-71-2 is a valid CAS Registry Number.
InChI:InChI=1/C13H16NOS.ClH/c1-11-13(7-8-15)16-10-14(11)9-12-5-3-2-4-6-12;/h2-6,10,15H,7-9H2,1H3;1H/q+1;
4568-71-2Relevant articles and documents
Benzothiazolium salt and having Hydroxyalykyl antistatic agent containing same
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Paragraph 0062, (2016/11/21)
PROBLEM TO BE SOLVED: To provide a thiazolium salt which possesses antistatic performance and whose cation is novel, and to provide an antistatic agent using the thiazolium salt. SOLUTION: The thiazolium salt is represented by formula (1) (wherein R1represents a hydrogen atom or a 1-20C alkyl group; R2represents a 1-20C alkyl group, a 2-20C alkenyl group, an aryl group, a 1-20C fluoroalkyl group, or a 7-20C aralkyl group; and R3represents a hydrogen atom or a 1-20C alkyl group; A-represents an anion, and n is an integer of 1 to 3). COPYRIGHT: (C)2013,JPOandINPIT
Method and composition for rejuvenating hair, nails, tissues, cells and organs by ex-vivo or immersive treatment
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, (2008/06/13)
A method and composition for the treatment of hair, nail, ex-vivo organ, ex-vivo cell or ex-vivo tissue to improve the biomechanical and diffusional characteristics comprising an effective amount of a compound selected from the group consisting of compounds of the formula
Preventing and reversing the formation of advanced glycosylation endproducts
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, (2008/06/13)
The present invention relates to compositions and methods for inhibiting and reversing nonenzymatic cross-linking (protein aging). Accordingly, compositions are disclosed which comprise an agent capable of inhibiting the formation of advanced glycosylation endproducts of target proteins, and which additionally reverse pre-formed crosslinks in the advanced glycosylation endproducts by cleaving alpha-dicarbonyl-based protein crosslinks present in the advanced glycosylation endproducts. Certain agents useful are thiazolium salts. The method comprises contacting the target protein with the composition. Both industrial and therapeutic applications for the invention are envisioned, as food spoilage and animal protein aging can be treated. A novel immunoassay for detection of the reversal of the nonenzymatic crosslinking is also disclosed.
