457-74-9Relevant articles and documents
Rhodium-Catalyzed Addition of Organozinc Iodides to Carbon-11 Isocyanates
Fouad, Moustafa H.,Ismailani, Uzair S.,Mair, Braeden A.,Munch, Maxime,Rotstein, Benjamin H.
supporting information, p. 2746 - 2750 (2020/04/16)
Amides were prepared using rhodium-catalyzed coupling of organozinc iodides and carbon-11 (11C, t1/2 = 20.4 min) isocyanates. Nonradioactive isocyanates and sp3 or sp2 organozinc iodides generated amides in yields of 13%-87%. Incorporation of cyclotron-produced [11C]CO2 into 11C-amide products proceeded in yields of 5%-99%. The synthetic utility of the methodology was demonstrated through the isolation of [11C]N-(4-fluorophenyl)-4-methoxybenzamide ([11C]6g) with a molar activity of 267 GBq μmol-1 and 12% radiochemical yield in 21 min from the beginning of synthesis.
An iron-catalysed synthesis of amides from nitriles and amines
Allen, C. Liana,Lapkin, Alexei A.,Williams, Jonathan M.J.
experimental part, p. 4262 - 4264 (2009/10/26)
The cheap, commercially available iron complex, Fe(NO3)3·9H2O, has been used to catalyse the formation of amides by the addition of amines to nitriles.
A novel synthesis of N-arylamides from nitroarenes via reductive N-acylation with red phosphorus and iodine
Du, Xiaohua,Zheng, Mei,Chen, Sheng,Xu, Zhenyuan
, p. 1953 - 1955 (2008/02/08)
A series of N-arylamides and imides were synthesized via reductive N-acylation of nitroarenes with red phosphorus and carboxylic acids, catalyzed by iodine or iodides; an I /I° redox cycle was proposed to promote the reaction. Georg Thieme Verlag Stuttgart.
