457889-95-1

Basic information

• Product Name: C₄₉H₇₆O₄Si₂
• Synonyms: C₄₉H₇₆O₄Si₂
• CAS NO: 457889-95-1
• Molecular Weight: 785.311
• Mol File: 457889-95-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₄₉H₇₆O₄Si₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₄₉H₇₆O₄Si₂(457889-95-1)
• EPA Substance Registry System: C₄₉H₇₆O₄Si₂(457889-95-1)

Safety Data

• Hazardous Substances Data: 457889-95-1(Hazardous Substances Data)

Upstream product

• 457889-90-6 C₃₆H₆₀O₄Si 
• 457889-89-3 (1S,2R,4aS,4bS,5R,6aR,9aS,10aS,10bS,12aS)-2-(tert-Butyl-dimethyl-silanyloxy)-5-hydroxy-1,4a,10a,10b-tetramethyl-7-(4-methyl-pent-3-enyl)-1,2,3,4,4a,4b,5,6,6a,9a,10,10a,10b,11,12,12a-hexadecahydro-9-oxa-pentaleno[2,1-a]phenanthren-8-one 
• 4701-54-6 (1S,2R,4aS,4bS,5R,6aR,9aS,10aS,10bS,12aS)-2,5-dihydroxy-1,4a,10a,10b-tetramethyl-7-(4-methylpent-3-en-1-yl)-1,2,3,4,4a,4b,5,6,6a,9a,10,10a,10b,11,12,12a-hexadecahydro-8H-naphtho[2′,1′:4,5]indeno[2,1-b]-furan-8-one 
• 3482-49-3 fusidine 
• 144-79-6 chloromethyldiphenylsilane 
• 457889-91-7 C₃₆H₆₄O₄Si 

Downstream Products

• 457889-92-8 C₅₁H₇₈O₅Si₂ 

Relevant articles and documents

17S,20S-Methanofusidic acid, a new potent semi-synthetic fusidane antibiotic.

A novel fusidic acid type antibiotic having the side chain linked to the tetracyclic ring system via a spiro-cyclopropane system is described. 17S,20S-Methanofusidic acid is obtained by an efficient synthetic route including cyclopropanation of the Delta17(20) bond with attack solely from the least hindered alpha-face. The spiro-cyclopropane system orients the side chain into a bioactive conformational space. The new 17S,20S-methanofusidic acid exerts antibacterial activity against several Gram-positive species with potency essentially equal to natural fusidic acid.