458566-99-9

Basic information

• Product Name: Methanesulfonic acid, trifluoro-, 4,5-dimethyl-2-(trimethylsilyl)phenyl ester
• CAS NO: 458566-99-9
• Molecular Formula: C12H17F3O3SSi
• Molecular Weight: 326.412
• Mol File: 458566-99-9.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Methanesulfonic acid, trifluoro-, 4,5-dimethyl-2-(trimethylsilyl)phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Methanesulfonic acid, trifluoro-, 4,5-dimethyl-2-(trimethylsilyl)phenyl ester(458566-99-9)
• EPA Substance Registry System: Methanesulfonic acid, trifluoro-, 4,5-dimethyl-2-(trimethylsilyl)phenyl ester(458566-99-9)

Safety Data

• Hazardous Substances Data: 458566-99-9(Hazardous Substances Data)

Usage

General Description

Methanesulfonic acid, trifluoro-, 4,5-dimethyl-2-(trimethylsilyl)phenyl ester is a chemical compound used in organic synthesis as a strong acid catalyst. It is known for its ability to promote various reactions such as esterifications, alkylations, and acylations, as well as for its compatibility with a wide range of functional groups. The compound is also utilized in the production of pharmaceuticals, agrochemicals, and specialty chemicals. Known for its high thermal stability and low volatility, it is a valuable tool for chemists working in the field of synthetic chemistry. Additionally, the compound is often used as a reagent for the introduction of the trifluoromethanesulfonyl (triflyl) group, which is an important functional group in medicinal chemistry, agrochemistry, and materials science. Despite its strong acidic nature, it is relatively stable and easy to handle, making it a popular choice for promoting a wide range of chemical reactions.

Upstream product

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Downstream Products

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Relevant articles and documents

The Versatility of the Aryne-Imine-Aryne Coupling for the -Synthesis of Acridinium Photocatalysts

The increasing use of acridinium photocatalysts as sustainable alternative to precious metal-based counterparts encourages the design and efficient synthesis of distinct catalyst structures. Herein, we report our exploration of the scope of the aryne-imin

Construction of Phenanthrenes and Chrysenes from β-Bromovinylarenes via Aryne Diels-Alder Reaction/Aromatization

A highly efficient transition-metal-free general method for the synthesis of polycyclic aromatic hydrocarbons like phenanthrenes and chrysenes (and tetraphene) from β-bromovinylarenes and arynes has been developed. The reactions proceed via an aryne Diels-Alder (ADA) reaction, followed by a facile aromatization. This is the first report on direct construction of chrysenes (and tetraphene) using the ADA approach. Unlike the literature method which is limited to only 9/10-substituted derivatives, this method gives access to a wide variety of functionalized phenanthrenes.

Transition-Metal-Free Benzannulation of Tricarbonyl Derivatives with Arynes: Access to 1,3-Dinaphthol Precursors for the Synthesis of Rhodamine Dye Analogues

Herein, we report a transition-metal-free annulation reaction of benzynes and 1,3-oxopentanedioate for the synthesis of highly functionalized naphthalene derivatives for the first time. Additionally, the representative naphthalene derivatives have been successfully transformed into the new series of rhodamine dye analogues.