459198-80-2

Basic information

• Product Name: 6-methyl-2-(2,4,6-trimethyl-phenylamino)-pyrimidin-4-ol
• Synonyms: 6-methyl-2-(2,4,6-trimethyl-phenylamino)-pyrimidin-4-ol
• CAS NO: 459198-80-2
• Molecular Weight: 243.308
• Mol File: 459198-80-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-methyl-2-(2,4,6-trimethyl-phenylamino)-pyrimidin-4-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methyl-2-(2,4,6-trimethyl-phenylamino)-pyrimidin-4-ol(459198-80-2)
• EPA Substance Registry System: 6-methyl-2-(2,4,6-trimethyl-phenylamino)-pyrimidin-4-ol(459198-80-2)

Safety Data

• Hazardous Substances Data: 459198-80-2(Hazardous Substances Data)

Upstream product

• 790689-27-9 N-(2,4,6-trimethyl-phenyl)-guanidine hydrochloride 
• 141-97-9 ethyl acetoacetate 

Downstream Products

• 864669-97-6 (4-chloro-6-methyl-pyrimidin-2-yl)-(2,4,6-trimethyl-phenyl)-amine 

Relevant articles and documents

PYRROLOPYRIMIDINE DERIVATIVES

According to the present invention, there is provided an antagonist against CRF receptors which is effective as a therapeutic or prophylactic agent for diseases in which CRF is considered to be involved, such as depression, anxiety, Alzheimer's disease, Parkinson's disease, Huntington's chorea, eating disorder, hypertension, gastro-intesinal diseases, drug dependence, cerebral infarction, cerebral ischemia, cerebral edema, cephalic external wound, inflammation, immunity-related diseases, alpecia, irritable bowel syndrome, sleep disorders, epilepsy, dermatitides, schizophrenia, pain, etc. A pyrrolopyrimidine derivative represented by the following formula [I]: has a high affinity for CRF receptors and is effective against diseases in which CRF is considered to be involved.