459448-16-9

Basic information

• Product Name: Ethyl 3-(4-phenylpiperazin-1-ylmethyl)-1H-indole-2-carboxylate
• Synonyms: Ethyl 3-(4-phenylpiperazin-1-ylmethyl)-1H-indole-2-carboxylate
• CAS NO: 459448-16-9
• Molecular Weight: 363.459
• Mol File: 459448-16-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Ethyl 3-(4-phenylpiperazin-1-ylmethyl)-1H-indole-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 3-(4-phenylpiperazin-1-ylmethyl)-1H-indole-2-carboxylate(459448-16-9)
• EPA Substance Registry System: Ethyl 3-(4-phenylpiperazin-1-ylmethyl)-1H-indole-2-carboxylate(459448-16-9)

Safety Data

• Hazardous Substances Data: 459448-16-9(Hazardous Substances Data)

Upstream product

• 92-54-6 4-phenyl-1-piperazine 
• 18450-27-6 ethyl 3-formyl-1H-indole-2-carboxylate 

Downstream Products

• 459448-36-3 3-(4-Phenylpiperazin-1-ylmethyl)-1H-indole-2-carbaldehyde 
• 459448-35-2 [3-(4-Phenylpiperazin-1-ylmethyl)-1H-indol-2-yl]-methanol 

Relevant articles and documents

Phenylpiperazinylmethylindolecarboxylates and derivatives as selective D(4)-ligands.

Novel phenylpiperazinylmethylindolecarboxylates were synthesized for evaluation as potential D(4)-ligands. Test compounds showed high affinity for the human dopamine D(4) receptor and great selectivity over the other receptor subtypes. Intrinsic effects of indole derivatives, which indicated most promising binding properties, were investigated in a mitogenesis assay.