459809-23-5Relevant articles and documents
Novel 2-(substituted phenyl)benzimidazole derivatives with potent activity against IgE, cytokines, and CD23 for the treatment of allergy and asthma
Richards, Mark L.,Lio, Shirley Cruz,Sinha, Anjana,Tieu, Kenneth K.,Sircar, Jagadish C.
, p. 6451 - 6454 (2004)
The effectiveness of the injectable anti-IgE antibody omalizumab has validated IgE as an important target for allergic diseases, thus spawning the development of small-molecule IgE inhibitors. Herein, a brief SAR is described for novel phenylbenzimidazole