461019-79-4Relevant articles and documents
Spirodiketopiperazine-based CCR5 antagonists: Lead optimization from biologically active metabolite
Nishizawa, Rena,Nishiyama, Toshihiko,Hisaichi, Katsuya,Matsunaga, Naoki,Minamoto, Chiaki,Habashita, Hiromu,Takaoka, Yoshikazu,Toda, Masaaki,Shibayama, Shiro,Tada, Hideaki,Sagawa, Kenji,Fukushima, Daikichi,Maeda, Kenji,Mitsuya, Hiroaki
, p. 727 - 731 (2007)
Hydroxylated derivatives were designed and synthesized based on the information of oxidative metabolites. Compounds derived from β-substituted (2R,3R)-2-amino-3-hydroxypropionic acid showed improved inhibitory activities against the binding of MIP-1α to h
DRUGS CONTAINING TRIAZASPIRO 5.5]UNDECANE DERIVATIVES AS THE ACTIVE INGREDIENT
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Page 288-289, (2010/02/05)
A pharmaceutical composition for prevention and/or treatment for HIV infection or AIDS induced by the infection which comprises, as an active ingredient, a triazaspiro[5.5]undecane derivative, a quaternary ammonium salt thereof, an N-oxide thereof, or a n
