4620-67-1

Basic information

• Product Name: 1-Phenylcyclobutanecarbonyl chloride
• Synonyms: 1-Phenylcyclobutanecarbonyl chloride;1-(Chlorocarbonyl)-1-phenylcyclobutane;1-Phenylcyclobutane-1-carbonyl chloride
• CAS NO: 4620-67-1
• Molecular Formula: C₁₁H₁₁ClO
• Molecular Weight: 194.66
• Product Categories: Carbonyl Chlorides;Phenyls & Phenyl-Het
• Mol File: 4620-67-1.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Sensitive: Moisture Sensitive
• CAS DataBase Reference: 1-Phenylcyclobutanecarbonyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Phenylcyclobutanecarbonyl chloride(4620-67-1)
• EPA Substance Registry System: 1-Phenylcyclobutanecarbonyl chloride(4620-67-1)

Safety Data

• HazardClass: 8
• Hazardous Substances Data: 4620-67-1(Hazardous Substances Data)

Usage

Physical state

Colorless to pale yellow liquid

Uses

Organic synthesis reactant, pharmaceutical preparation, agrochemical production, dyes and pigments production

Industry applications

Versatile building block, intermediate in pharmaceutical industry

Safety precautions

Potential irritant, handle with care, requires well-ventilated area and appropriate protective equipment.

Upstream product

• 140-29-4 phenylacetonitrile 
• 79-37-8 oxalyl dichloride 
• 37828-19-6 1-(phenyl)cyclobutane-1-carboxylic acid 
• 14377-68-5 1-phenylcyclobutanecarbonitrile 

Downstream Products

• 1534433-47-0 2-(4-methoxyphenyl)-1-phenyl-N-(quinolin-8-yl)cyclobutanecarboxamide 
• 1240806-35-2 1-phenyl-N-(quinolin-8-yl)cyclobutanecarboxamide 
• 1354042-80-0 C₂₈H₂₄FN₇O₂ 
• 1332720-09-8 C₂₀H₁₇F₃N₄O 
• 38117-54-3 cyclopentadienyl iron(II) dicarbonyl dimer 
• 202736-61-6 (1-Methyl-3-piperidino)methyl 1-phenylcyclobutanecarboxylate Hydrochloride 
• 202736-60-5 (1-Methyl-2-piperidino)methyl 1-phenylcyclobutanecarboxylate Hydrochloride 
• 202736-59-2 2-(1-Pyrrolidino)ethyl 1-phenylcyclobutanecarboxylate Hydrochloride 

Relevant articles and documents

Amide compound and derivative thereof, preparation method, pharmaceutical composition and application thereof

The invention discloses an amide compound and derivative thereof, a preparation method, a pharmaceutical composition and application thereof. The structure of the amide compound is shown as a formula (I). The derivatives of theamide compound relate to a stereoisomer, a tautomer, a metabolite, a metabolic precursor, a prodrug, a solvate, a salt of the solvate, a crystal, a pharmaceutically acceptable salt or a mixture of the above of theamide compound. The amide compound and the derivative thereof have an efficient inhibition effect on indoleamine 2, 3-dioxygenase 1, and can be used for preparing medicines for treating indoleamine 2, 3-dioxygenase 1 mediated immunosuppression related diseases, the prepared medicine can exert the medicine effect at the molecular level and is wide in application, and the synthesis method of the compound is simple, convenient and easy to operate.