4640-44-2

Basic information

• Product Name: 3-aminocyclobutanol(SALTDATA: FREE)
• Synonyms: 3-aminocyclobutanol(SALTDATA: FREE);Cyclobutanol, 3-aMino-;3-aminocyclobutan-1-ol;3-Aminocyclobutanol hydrochloride - A0319
• CAS NO: 4640-44-2
• Molecular Formula: C₄H₉NO
• Molecular Weight: 123.5813
• Mol File: 4640-44-2.mol
• Article Data: 1

Chemical Properties

• Melting Point: >300 °C
• Boiling Point: 158℃
• Flash Point: 49℃
• Appearance: /
• Density: 1.153
• Storage Temp.: 2-8°C(protect from light)
• PKA: 15.00±0.40(Predicted)
• CAS DataBase Reference: 3-aminocyclobutanol(SALTDATA: FREE)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-aminocyclobutanol(SALTDATA: FREE)(4640-44-2)
• EPA Substance Registry System: 3-aminocyclobutanol(SALTDATA: FREE)(4640-44-2)

Safety Data

• RIDADR: 1760
• HazardClass: 8
• PackingGroup: Ⅲ
• Hazardous Substances Data: 4640-44-2(Hazardous Substances Data)

Usage

General Description

3-aminocyclobutanol, also known as SALTDATA: FREE, is a chemical compound with the molecular formula C4H9NO. It is a cyclic compound with a four-membered ring containing an amino group and an alcohol functional group. 3-aminocyclobutanol(SALTDATA: FREE) is used in organic synthesis as a building block for the preparation of various pharmaceuticals and bioactive molecules. The chemical properties of 3-aminocyclobutanol make it a versatile intermediate in the production of a broad range of compounds. It is also used in academic research and development in the field of organic chemistry. Overall, 3-aminocyclobutanol is an important chemical with potential applications in various industries.

Upstream product

• 92146-77-5 3-amino-1-benzyloxycyclobutane 

Downstream Products

• 395074-78-9 3-(4-nitro-1H-imidazol-1-yl)cyclobutanol 
• 18126-77-7 3-(dimethylamino)cyclobutan-1-ol 
• 1572513-27-9 C₁₈H₁₉FN₂O₄S 
• 1572513-30-4 C₁₈H₁₉FN₂O₄S 

Relevant articles and documents

Potent and cellularly active 4-aminoimidazole inhibitors of cyclin-dependent kinase 5/p25 for the treatment of Alzheimer's disease

Utilizing structure-based drug design, a 4-aminoimidazole heterocyclic core was synthesized as a replacement for a 2-aminothiazole due to potential metabolically mediated toxicity. The synthetic route utilized allowed for ready synthesis of 1-substituted-4-aminoimidazoles. SAR exploration resulted in the identification of a novel cis-substituted cyclobutyl group that gave improved enzyme and cellular potency against cdk5/p25 with up to 30-fold selectivity over cdk2/cyclin E.