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465-65-6 Usage

Chemical Description

Naloxone is an opioid antagonist that can reverse the effects of opioids such as morphine.

Check Digit Verification of cas no

The CAS Registry Mumber 465-65-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,6 and 5 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 465-65:
(5*4)+(4*6)+(3*5)+(2*6)+(1*5)=76
76 % 10 = 6
So 465-65-6 is a valid CAS Registry Number.

InChI:InChI=1/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1

465-65-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name	naloxone

1.2 Other means of identification

Product number	-
Other names	Narcon

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:465-65-6 SDS

465-65-6Upstream product

465-65-6Downstream Products

465-65-6Relevant articles and documents

Studies of 3-O-acyl derivatives of naloxone as its potential prodrugs

Ukrainets,Tkach,Gorokhova,Turov,Linsky

, p. 405 - 416 (2009)

An efficient method has been proposed for the preparation of a series of 3-O-acyl derivatives of naloxone. The features of the steric structure and NMR spectra are discussed. Pharmaceutical investigation has shown the promise within the synthesized compou

PROCESS FOR THE PREPARATION OF MORPHINANE COMPOUNDS

-

Page/Page column 9, (2019/01/21)

The invention describes the process of catalytic O-demethylation of 3-methoxy-morphinane compounds using boron tribromide. Addition of catalysts reduces the reaction time, improves reacting the substrate to give the product in very good purity and yield. The said approach can be used, for example, for the preparation of oxymorphone, naltrexone, naloxone and nalbuphine from their respective O-methyl derivatives.

REDUCTION OF ALPHA, BETA-UNSATURATED KETONE LEVELS IN MORPHINAN DERIVATIVE COMPOSITIONS

-

Page/Page column 00577; 00578; 00579, (2016/04/26)

The disclosure relates to processes for reducing the amount of a compound of formula (I) or a salt or a solvate thereof present in a composition comprising compounds of formulae (I) and (II) or a salt or a solvate thereof.

CAS

465-65-6