4664-00-0

Basic information

• Product Name: QUINOLINIMIDE
• Synonyms: 2,3-PYRIDINEDICARBOXAMIDE;AKOS 93366;5H-PYRROLO[3,4-B]PYRIDINE-5,7(6H)-DIONE;QUINOLINIMIDE;PYRROLO[3,4-B]PYRIDINE-5,7-DIONE;2,3-pyridinedicarboximide;3-azaphthalimid;pyridinedicarboxamide
• CAS NO: 4664-00-0
• Molecular Formula: C₇H₄N₂O₂
• Molecular Weight: 148.12
• EINECS: 225-107-1
• Product Categories: Pyridine;Miscellaneous Reagents;Aromatics;Heterocycles;Heterocycle-Pyridine series
• Mol File: 4664-00-0.mol
• Article Data: 17

Chemical Properties

• Melting Point: 233-234°C
• Boiling Point: 268.69°C (rough estimate)
• Appearance: Light yellow solid
• Density: 1.4015 (rough estimate)
• Refractive Index: 1.5300 (estimate)
• Storage Temp.: Refrigerator
• Solubility: Dichloromethane, Ether, Ethyl Acetate, Methanol
• PKA: 8.08±0.20(Predicted)
• CAS DataBase Reference: QUINOLINIMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: QUINOLINIMIDE(4664-00-0)
• EPA Substance Registry System: QUINOLINIMIDE(4664-00-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• Hazardous Substances Data: 4664-00-0(Hazardous Substances Data)

Usage

Chemical Properties

Light yellow solid

Uses

Quinolinimide (cas# 4664-00-0) is a compound useful in organic synthesis.

InChI:InChI=1/C7H4N2O2/c10-6-4-1-2-8-3-5(4)7(11)9-6/h1-3H,(H,9,10,11)

Upstream product

• 699-98-9 Pyridine-2,3-dicarboxylic anhydride 
• 89-00-9 Pyridine-2,3-dicarboxylic acid 
• 108-24-7 acetic anhydride 
• 73112-09-1 2-cyanopyridine-3-carboxylic acid 
• 4663-94-9 pyridine-2,3-dicarboxamide 
• 57-13-6 urea 
• 60-35-5 acetamide 

Downstream Products

• 4663-94-9 pyridine-2,3-dicarboxamide 
• 1462-86-8 3-amino-pyridine-2-carboxylic acid 
• 115012-09-4 6,7-Dihydro-7-hydroxy-5H-pyrrolo<3,4-b>pyridin-5-one 
• 115012-10-7 5,6-dihydro-5-hydroxy-7H-pyrrolo<3,4-b>pyridin-7-one 
• 115012-11-8 2-(hydroxymethyl)nicotinamide 
• 115012-12-9 3-hydroxymethyl-2-pyridinecarboxamide 
• 6789-51-1 6-methyl-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione 
• 18184-75-3 6-benzyl-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione 
• 120347-89-9 6-benzyl-6,7-dihydro-7-hydroxypyrrolo<3,4-b>pyridin-5-one 
• 442882-27-1 6-(4-methoxybenzyl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione 
• 158060-81-2 2,8-diazabicyclo[4.3.0]nonane 
• 128740-14-7 (R,R)-8-benzyl-2,8-diazabicyclo[4.3.0]-nonane 
• 5654-94-4 2,8-diazabicyclo-[4.3.0]-nonane 

Relevant articles and documents

Method for preparing 6,7-dihydro-5H-pyrrolo-pyridine hydrochloride

The invention discloses a preparation method for preparing 6,7-dihydro-5H-pyrrolo-pyridine hydrochloride. The method is characterized in that a target product 6,7-dihydro-5H-pyrrolo-pyridine hydrochloride is obtained through lactamization, reduction and salifying by taking furo[3,4-b]pyridine-5,7-dione as an original raw material. The compound is an important medical intermediate.

New artificial fluoro-cofactor of hydride transfer with novel fluorescence assay for redox biocatalysis

A new artificial fluoro-cofactor was developed for the replacement of natural cofactors NAD(P), exhibiting a high hydride transfer ability. More importantly, we established a new and fast screening method for the evaluation of the properties of artificial cofactors based on the fluorescence assay and visible color change.

Method for preparing 6-(1-phenyl-ethyl)-pyrrolo[3,4-b]pyridine-5,7-dione

The invention more specifically relates to a method for preparing 6-(1-phenyl-ethyl)-pyrrolo[3,4-b]pyridine-5,7-dione. The preparation method comprises the following steps: 5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione is generated from 2,3-dipicolinic acid and urea, ethylbenzene and hydrogen halide are reacted in order to generate (1-haloethyl)benzene, (1-haloethyl)benzene and 2,3-dipicolinic acid are generated into a crude product, and finally a target compound is obtained by chiral separation. The method is advantageous in that the synthesis technology has the advantages of mild reaction condition, short reaction time, high yield without generation of harmful refuses, simple post-treatment, recycling of 1,2-dichloroethane solvent which is separated from the reaction process, and easy industrialization.