4677-09-2 Usage
Molecular structure
1,3,3-trimethyl-2-[(phenylazo)methylene]indoline consists of a tricyclic indoline ring system with a phenylazo group attached.
Indoline ring
A tricyclic ring system with a nitrogen atom in the seven-membered ring.
Phenylazo group
A phenyl group (C6H5) connected to a nitrogen atom through a double bond (-N=).
Color properties
The compound exhibits vibrant and intense colors due to the presence of the phenylazo group, which allows it to absorb and emit certain wavelengths of light.
Dye
Used in various applications, such as coloring textiles, plastics, and other materials.
Organic synthesis
Potential applications in the synthesis of other organic compounds.
Materials science
Potential use in the development of new materials due to its unique structure.
Research interest
The unique structure of 1,3,3-trimethyl-2-[(phenylazo)methylene]indoline makes it a subject of interest in various chemical and biological studies.
Solubility
The compound is likely to be soluble in organic solvents, such as ethanol, methanol, or acetone, due to its nonpolar nature.
Stability
1,3,3-trimethyl-2-[(phenylazo)methylene]indoline is expected to be stable under normal conditions, but may be sensitive to light, heat, or strong acids and bases.
Safety
As with any chemical compound, proper handling and storage are necessary to minimize risks. It is important to follow safety guidelines and use appropriate personal protective equipment when working with this compound.
Synthesis
The synthesis of 1,3,3-trimethyl-2-[(phenylazo)methylene]indoline typically involves the formation of the indoline ring system followed by the attachment of the phenylazo group through a condensation reaction.
Check Digit Verification of cas no
The CAS Registry Mumber 4677-09-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,6,7 and 7 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 4677-09:
(6*4)+(5*6)+(4*7)+(3*7)+(2*0)+(1*9)=112
112 % 10 = 2
So 4677-09-2 is a valid CAS Registry Number.
InChI:InChI=1/C18H19N3/c1-18(2)15-11-7-8-12-16(15)21(3)17(18)13-19-20-14-9-5-4-6-10-14/h4-13H,1-3H3/b17-13+,20-19+
4677-09-2Relevant articles and documents
Antimicrobial and cytotoxic arylazoenamines. Part III: Antiviral activity of selected classes of arylazoenamines
Tonelli, Michele,Boido, Vito,Canu, Caterina,Sparatore, Anna,Sparatore, Fabio,Paneni, Maria Silvia,Fermeglia, Maurizio,Pricl, Sabrina,La Colla, Paolo,Casula, Laura,Ibba, Cristina,Collu, David,Loddo, Roberta
experimental part, p. 8447 - 8465 (2009/04/11)
Eighty-five arylazoenamines, characterized by different types of aryl and basic moieties, have been synthesized and evaluated in cell-based assays for cytotoxicity and antiviral activity against a panel of ten RNA and DNA viruses. The most commonly affected viruses were, in decreasing order, CVB-2, RSV, BVDV, YFV, and Sb-1; the remaining viruses were either not affected (HIV-1, VSV, and VV) or susceptible only to a very few compounds (Reo-1 and HSV-1). Thirty-five compounds exhibited high activity, with EC50 in the range 0.8-10 μM, and other 28 compounds had EC50 between 11 and 30 μM, thus indicating that the arylazoenamine molecular pattern is an interesting novel pharmacophore for antiviral agents against ssRNA viruses. Moreover, some compounds (as 28, 32, 42, and 53) appear of high interest, being devoid of toxicity on the human MT-4 cells (CC50 > 100 μM). A ligand-based computational approach was employed to identify highly predictive pharmacophore models for the most frequently affected viruses CVB-2, RSV, and BVDV. These models should allow the design of second generation of more potent inhibitors of these human and veterinary pathogens.
