4679-90-7

Basic information

• Product Name: 1H-Isoindol-1-one, 2,3-dihydro-2-phenyl-3-(phenylmethyl)-
• CAS NO: 4679-90-7
• Molecular Formula: C21H17NO
• Molecular Weight: 299.36600
• Mol File: 4679-90-7.mol
• Article Data: 4

Chemical Properties

• Melting Point: 124-125 °C
• Boiling Point: 462.9±38.0 °C(Predicted)
• Density: 1.204±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1H-Isoindol-1-one, 2,3-dihydro-2-phenyl-3-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Isoindol-1-one, 2,3-dihydro-2-phenyl-3-(phenylmethyl)-(4679-90-7)
• EPA Substance Registry System: 1H-Isoindol-1-one, 2,3-dihydro-2-phenyl-3-(phenylmethyl)-(4679-90-7)

Safety Data

• Hazardous Substances Data: 4679-90-7(Hazardous Substances Data)

Usage

Appearance

White to light yellow solid at room temperature

Derivative of

Isatin

Potential pharmacological activities

+ Monoamine oxidase inhibitor (useful in the treatment of depression and other mood disorders)
+ Anticonvulsant properties
+ Analgesic properties

Need for further studies

To fully understand the potential therapeutic applications of the compound.

Upstream product

• 82971-76-4 (Z)-2-phenyl-3-(phenylmethylene)isoindolin-1-one 
• 86770-00-5 (E)-N-phenyl-2-styrylbenzamide 
• 907174-66-7 C₁₅H₁₁ClO 
• 62-53-3 aniline 
• 60901-21-5 o-styrylbenzoic acid 
• 63104-88-1 Methyl 2-styrylbenzoate 
• 100-42-5 styrene 
• 610-97-9 o-iodo-methyl-benzoic acid 
• 82971-74-2 N-phenyl-2-(2-phenylethynyl)benzamide 
• 15310-01-7 benodanil 

Relevant articles and documents

Novel synthetic method of 3,4-dihydroisoquinolin-1-one and isoindolin-1-one derivatives

The invention relates to a synthetic method of 3,4-dihydroisoquinolin-1-one and isoindolin-1-one derivatives; particularly, a base is added to 2-allyl-benzamide serving as a raw material under the protection of nitrogen, and heating is performed in a solvent to obtain dihydroisoquinolin-1-one or isoindolin-1-one compounds under high yield. The synthetic method is simple to perform, high in reaction yield and low in usage of bases in reaction, has no need for using transition metal catalysts, and is highly worthy of application in the industrial preparation of isoindolin-1-one compounds.

Novel chemoselective desulfurization of γ-phenylthio-substituted aromatic lactams: Application to the synthesis of isoindolobenzazepine alkaloid, lennoxamine

Treatment of a variety of γ-phenylthio-substituted aromatic lactams with lithium aluminum hydride in the presence of cuprous iodide led to novel chemoselective desulfurization reactions to afford the corresponding substituted aromatic lactams without givi