470-38-2 Usage
Description
(3S,3'S,5R,5'R)-3,3'-dihydroxy-.kappa.,.kappa.-carotene-6,6'-dione, also known as Capsorubin, is a carotenoid pigment and a metabolite of a Xanthophyll (X742000) with a unique structure containing unusual five-membered ring end groups. It is derived from red peppers (Capsicum annuum) and has been found to possess various beneficial properties, including antioxidant, antinociceptive, and anti-inflammatory effects.
Uses
Used in Pharmaceutical Industry:
Capsorubin is used as a pharmaceutical agent for its antioxidant, antinociceptive, and anti-inflammatory properties. These characteristics make it a promising candidate for the development of drugs targeting various health conditions, such as inflammation, pain, and oxidative stress-related diseases.
Used in Nutraceutical Industry:
Due to its antioxidant properties, Capsorubin is also used in the nutraceutical industry as a supplement to promote overall health and well-being. It can be incorporated into dietary supplements and functional foods to enhance their health benefits.
Used in Cosmetic Industry:
Capsorubin's antioxidant and anti-inflammatory properties also make it a valuable ingredient in the cosmetic industry. It can be used in skincare products to help protect the skin from environmental stressors, reduce inflammation, and promote a healthy, youthful appearance.
Purification Methods
Possible impurities are zeaxanthin and capsanthin. Purify capsorubin by chromatography on a column of CaCO3 or MgO. Crystallise it from *benzene/pet ether or CS2. [Beilstein 1
Check Digit Verification of cas no
The CAS Registry Mumber 470-38-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,7 and 0 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 470-38:
(5*4)+(4*7)+(3*0)+(2*3)+(1*8)=62
62 % 10 = 2
So 470-38-2 is a valid CAS Registry Number.
470-38-2Relevant articles and documents
Total synthesis of capsanthin and capsorubin using Lewis acid-promoted regio- and stereoselective rearrangement of tetrasubsutituted epoxides
Yamano, Yumiko,Ito, Masayoshi
, p. 3207 - 3212 (2008/03/14)
The synthesis of capsanthin 1 and capsorubin 2 was accomplished via the C15-cyclopentyl ketone 6 prepared by Lewis acid-promoted regio- and stereoselective rearrangement of the epoxy dienal 5. The Royal Society of Chemistry.
Carotenoids and Related Compounds. Part 37. Stereochemistry and Synthesis of Capsorubin
Bowden, Roy D.,Cooper, Robin D. G.,Harris, C. John,Moss, Gerard P.,Weedon, Basil C. L.,Jackman, Lloyd M.
, p. 1465 - 1474 (2007/10/02)
The two oxygen substitutents in the end groups of capsorubin were shown to be trans to one another by synthesis of optically inactive forms of the carotenoid, and of the isomers which have the corresponding cis-structure.The 3S,5R,3'S,5'R configuration thus established for the natural carotenoid was confirmed by synthesis of this stereoisomer from (+)-camphor.Cryptocapsin has the 3'S,5'R configuration, and the racemic form has been synthesised.Capsanthin has the 3R,3'S,5'R configuration.