4707-24-8

Basic information

• Product Name: 4-BROMO-2,3,5,6-TETRAFLUOROBENZOIC ACID
• Synonyms: 4-BROMO-2,3,5,6-TETRAFLUOROBENZOIC ACID;RARECHEM AL BO 0688;4-Bromo-2,3,5,6-tetrafluorobenzoic acid 98%;4-Bromo-2,3,5,6-tetrafluorobenzoicacid98%;4-Bromo-2,3,5,6-tetrafluoroben;4-Bromo-2,3,5,6-tetrafluorobenzoic acid, 97+%;4-Bromo-2,3,5,6-tetrafluorobenzoic acid, 95+%;Perfluoro-4-bromobenzoic acid 98%
• CAS NO: 4707-24-8
• Molecular Formula: C₇HBrF₄O₂
• Molecular Weight: 272.98
• Product Categories: C7;Carbonyl Compounds;Carboxylic Acids
• Mol File: 4707-24-8.mol
• Article Data: 4

Chemical Properties

• Melting Point: 142-145 °C(lit.)
• Boiling Point: 260.9 °C at 760 mmHg
• Flash Point: 111.6 °C
• Appearance: /
• Density: 2.022 g/cm³
• Refractive Index: 1.519
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 1.43±0.10(Predicted)
• Water Solubility: Insoluble in water.
• CAS DataBase Reference: 4-BROMO-2,3,5,6-TETRAFLUOROBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-2,3,5,6-TETRAFLUOROBENZOIC ACID(4707-24-8)
• EPA Substance Registry System: 4-BROMO-2,3,5,6-TETRAFLUOROBENZOIC ACID(4707-24-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• Hazardous Substances Data: 4707-24-8(Hazardous Substances Data)

Usage

Chemical Properties

White solid

Uses

4-Bromo-2,3,5,6-tetrafluorobenzoic acid is used as a pharmaceutical intermediate.

InChI:InChI=1/C7H2BrF4NO/c8-2-5(11)3(9)1(7(13)14)4(10)6(2)12/h(H2,13,14)

Upstream product

• 344-03-6 1,4-dibromotetrafluorobenzene 
• 124-38-9 carbon dioxide 
• 944-43-4 4-amino-2,3,5,6-tetrafluorobenzoic acid 
• 7789-45-9 copper(II)bromide 

Downstream Products

• 122033-54-9 4-bromo-2,3,5,6-tetrafluorobenzoyl chloride 
• 1307892-43-8 C₄H₅N₃*C₇HBrF₄O₂ 
• 1307892-45-0 C₄H₄BrN₃*C₇HBrF₄O₂ 
• 1307892-47-2 C₄H₃Br₂N₃*C₇HBrF₄O₂ 
• 1416042-62-0 C₂₁H₁₆N₂*C₇HBrF₄O₂ 
• 4707-23-7 4-bromo-2,3,5,6-tetrafluoro-benzoic acid methyl ester 
• 652-36-8 2,3,5,6-tetrafluoroterephthalic acid 
• 123942-19-8 ethyl 1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-(2,6-dimethyl-4-pyridinyl)-6-fluoro-4-oxo-5-<(phenylmethyl)thio>-3-quinolinecarboxylate 
• 123942-22-3 ethyl 1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-(2,6-dimethyl-4-pyridinyl)-6-fluoro-4-oxo-5-(phenylthio)-3-quinolinecarboxylate 
• 123942-18-7 (Z)-2-(4-Bromo-2,3,5,6-tetrafluoro-benzoyl)-3-cyclopropylamino-acrylic acid ethyl ester 
• 123942-17-6 (Z)-2-(4-Bromo-2,3,5,6-tetrafluoro-benzoyl)-3-dimethylamino-acrylic acid ethyl ester 
• 122033-55-0 3-(4-Bromo-2,3,5,6-tetrafluoro-phenyl)-3-oxo-propionic acid ethyl ester 
• 123942-05-2 1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-(2,6-dimethyl-4-pyridinyl)-4-oxo-3-quinolinecarboxylic acid 

Relevant articles and documents

Facile synthesis and supramolecular chemistry of hydrogen bond/halogen bond-driven multi-tasking tectons

Hydrogen bonds and halogen bonds can be used as synthetic vectors without structural interference as long as the primary molecular recognition events are designed around a careful combination of geometric and electrostatic complementarity. In addition, a one-step procedure for the synthesis of tectons equipped with powerful hydrogen- and halogen-bond donors is presented. The Royal Society of Chemistry 2011.

Pyridinyl-quinolone compounds, their preparation and use

Fluorinated 1-cyclopropyl-7-(substituted-pyridinyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids of the formula STR1 wherein R is hydrogen, R' and R" are hydrogen or fluoro, or other groups and Z is 3- or 4-pyridinyl substituted by alkyl groups or substituted alkyl groups, are superior antibacterial agents. They are prepared via a coupling reaction between the corresponding esters (R=alkyl) having a halo group in the 7-position and a substituted (trialkylstannyl)pyridine.