4708-96-7

Basic information

• Product Name: 7-Monodemethyl Minocycline
• Synonyms: 4S-(4α,4aα,5aα,12aα)]-4-(DiMethylaMino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-7-(MethylaMino)-1,11-dioxo-2-naphthacenecarboxaMide;Minocycline EP IMpurity C;4S-(4a,4aa,5aa,12aa)]-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-7-(methylamino)-1,11-dioxo-2-naphthacenecarboxamide;7-Methylamino-6-deoxy-6-demethyltetracycline;7-Monodemethyl Minocycline;Unii-fyy3R43wgo;7-Monodemethyl Minocycline DISCONTINUED;(4S,4aS,5aR,12aS)-4-(Dimethylamino)-3,10,12,12a-tetrahydroxy-7-(methylamino)-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
• CAS NO: 4708-96-7
• Molecular Formula: C22H25N3O7
• Molecular Weight: 443.453
• Product Categories: Various Metabolites and Impurities;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
• Mol File: 4708-96-7.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 805.5°C at 760 mmHg
• Flash Point: 440.9°C
• Appearance: /
• Density: 1.58g/cm³
• Vapor Pressure: 2.15E-27mmHg at 25°C
• Refractive Index: 1.726
• CAS DataBase Reference: 7-Monodemethyl Minocycline(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Monodemethyl Minocycline(4708-96-7)
• EPA Substance Registry System: 7-Monodemethyl Minocycline(4708-96-7)

Safety Data

• Hazardous Substances Data: 4708-96-7(Hazardous Substances Data)

Usage

Description

7-Monodemethyl Minocycline is a derivative of Minocycline, a second-generation tetracycline antibiotic. It is characterized by the removal of one methyl group from the Minocycline molecule, which results in the alteration of its chemical properties and potential applications. 7-Monodemethyl Minocycline exhibits neuroprotective properties, making it a promising candidate for various therapeutic applications.

Uses

Used in Pharmaceutical Industry:
7-Monodemethyl Minocycline is used as an impurity in the production of Minocycline (M344800), a second-generation tetracycline antibiotic. Its presence in the manufacturing process is essential for the development of the antibiotic's therapeutic effects.
Used in Neuroprotection:
7-Monodemethyl Minocycline is used as a neuroprotective agent due to its ability to protect neurons from damage and degeneration. This property makes it a potential candidate for the treatment of various neurological disorders, such as neurodegenerative diseases and conditions involving neuronal damage.
Used in Research and Development:
7-Monodemethyl Minocycline is used as a research compound to study the effects of Minocycline and its derivatives on various biological processes. Its unique properties allow scientists to explore its potential applications in drug development and therapeutic interventions.

InChI:InChI=1/C22H25N3O7/c1-24-11-4-5-12(26)14-9(11)6-8-7-10-16(25(2)3)18(28)15(21(23)31)20(30)22(10,32)19(29)13(8)17(14)27/h4-5,8,10,16,24,26,28-29,32H,6-7H2,1-3H3,(H2,23,31)