4731-34-4

Basic information

• Product Name: 1-METHYL-2-(2-METHYLPHENOXY)BENZENE
• Synonyms: 1-METHYL-2-(2-METHYLPHENOXY)BENZENE;di-o-tolyl ether;1,1'-Oxybis[2-methylbenzene];2-(2-Methylphenoxy)-1-methylbenzene;2,2'-Dimethyldiphenyl ether;Bis(2-methylphenyl) ether
• CAS NO: 4731-34-4
• Molecular Formula: C₁₄H₁₄O
• Molecular Weight: 198.26
• EINECS: 225-233-7
• Mol File: 4731-34-4.mol
• Article Data: 25

Chemical Properties

• Boiling Point: 271°C (estimate)
• Flash Point: 114.3°C
• Appearance: /
• Density: 1.0470
• Refractive Index: 1.5948 (estimate)
• CAS DataBase Reference: 1-METHYL-2-(2-METHYLPHENOXY)BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-METHYL-2-(2-METHYLPHENOXY)BENZENE(4731-34-4)
• EPA Substance Registry System: 1-METHYL-2-(2-METHYLPHENOXY)BENZENE(4731-34-4)

Safety Data

• Hazardous Substances Data: 4731-34-4(Hazardous Substances Data)

Usage

Also known as

1,2-dimethyl-3-phenoxybenzene

Aromatic compound

Yes

Explanation

It has a benzene ring in its chemical structure.

Explanation

The mass of one mole of the compound.

Explanation

The temperature range at which the compound changes from solid to liquid state.

Explanation

The appearance of the compound in its liquid form.

Explanation

The compound has a very mild or barely noticeable smell.

Explanation

The chemical is relatively safe, but should be handled with care and stored properly to prevent exposure and environmental contamination.

Chemical structure

Benzene ring substituted with a methyl group and a 2-methylphenoxy group

Usage

Production of chemical products such as dyes, fragrances, and pharmaceuticals

Molecular weight

208.30 g/mol

Melting point

30-32°C

Physical state

Colorless to pale yellow liquid

Odor

Faint

Toxicity

Not considered highly toxic or harmful

InChI:InChI=1/C14H14O/c1-11-7-3-5-9-13(11)15-14-10-6-4-8-12(14)2/h3-10H,1-2H3

Upstream product

• 95-48-7 ortho-cresol 
• 615-37-2 ortho-methylphenyl iodide 
• 95-46-5 2-methylphenyl bromide 
• 13859-13-7 o-cresol; aluminium (III)-compound 
• 583-60-8 2-Methylcyclohexanone 
• 5271-27-2 1-methyl-3-phenylpiperazine 
• 498-66-8 norborn-2-ene 
• 95-49-8 2-methylchlorobenzene 
• 16419-60-6 2-Methylphenylboronic acid 
• 10038-41-2 2,2'-bis(bromomethyl)-1,1'-oxybisbenzene 
• 95-53-4 o-toluidine 

Downstream Products

• 95-48-7 ortho-cresol 
• 108-88-3 toluene 
• 10038-41-2 2,2'-bis(bromomethyl)-1,1'-oxybisbenzene 
• 860573-00-8 3-methyl-4-(2-methylphenoxy)aniline 
• 89446-91-3 C₅₂H₄₀N₂OP₂⁽²⁺⁾*2Br^(1-) 
• 89446-96-8 4,4'-diamidino-2,2'-dimethyldiphenyl ether dihydrochloride 
• 89446-97-9 2,2'-dimethyldiphenyl ether-4,4'-diamidoxime 
• 89446-89-9 4,4'-dicyano-2,2'-dibromomethyldiphenyl ether 
• 89446-88-8 4,4'-dicyano-2,2'-dimethyldiphenyl ether 
• 86096-72-2 2,2'-Oxybis 
• 32852-70-3 2,2'-oxy-di-benzoyl chloride 
• 49589-41-5 (4-chloro-2-methyl-phenyl)-o-tolyl ether 
• 23886-18-2 4,4'-oxybis(3-methyl-1-nitrobenzene) 
• 1136-77-2 4,6-dimethyldibenzo[b,d]furan 

Relevant articles and documents

Access to Dibenzofurans through Dimerization/Trimerization of Cyclohexanones Followed by Dehydroaromatization

A novel and efficient method for the synthesis of unsymmetrical substituted dibenzofurans has been developed, which can selectively produce disubstituted dibenzofurans and trisubstituted dibenzofurans products under metal-free conditions. This approach starts from cheap and available nonaromatic cyclohexanones, affording a simple and efficient access to unsymmetrical substituted dibenzofurans.

Competing Pathways in O-Arylations with Diaryliodonium Salts: Mechanistic Insights

A mechanistic study of arylations of aliphatic alcohols and hydroxide with diaryliodonium salts, to give alkyl aryl ethers and diaryl ethers, has been performed using experimental techniques and DFT calculations. Aryne intermediates have been trapped, and additives to avoid by-product formation originating from arynes have been found. An alcohol oxidation pathway was observed in parallel to arylation; this is suggested to proceed by an intramolecular mechanism. Product formation pathways via ligand coupling and arynes have been compared, and 4-coordinated transition states were found to be favored in reactions with alcohols. Furthermore, a novel, direct nucleophilic substitution pathway has been identified in reactions with electron-deficient diaryliodonium salts.

Palladium-Catalyzed Sequential Acylation/Cyanation of Aryl Iodides: A Regiospecific Synthesis of 2-Cyanoaryl Ketones

A palladium-catalyzed, norbornene-mediated acylation/cyanation reaction of iodobenzene was developed by the use of acyl chlorides as acylation reagents and cuprous cyanide. The reaction gave the 2-cyanoaryl ketones efficiently by using readily available starting materials. (Chemical Equation Presented).