473537-92-7 Usage
Description
Benzenebutanoic acid, 3-brom-.alpha.,.gamma.-dioxo-, ethyl ester, also known as 3-bromo-1-(4-oxo-3-phenylbutyl)-3,4-dihydro-2H-1,4-benzoxazin-2-one, is an ester derivative of benzenebutanoic acid. It is a white to off-white powder with a molecular formula of C16H15BrO4 and a molecular weight of 345.2 g/mol. This chemical is typically used as a reagent in organic synthesis and is considered potentially hazardous, requiring proper safety precautions when handled in laboratory settings.
Uses
Used in Organic Synthesis:
Benzenebutanoic acid, 3-brom-.alpha.,.gamma.-dioxo-, ethyl ester is used as a reagent in organic synthesis for various chemical reactions. Its unique structure and functional groups allow it to participate in a range of reactions, making it a valuable component in the synthesis of complex organic molecules and pharmaceutical compounds.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Benzenebutanoic acid, 3-brom-.alpha.,.gamma.-dioxo-, ethyl ester is used as an intermediate in the synthesis of drugs and drug candidates. Its versatility in organic synthesis enables the creation of new molecules with potential therapeutic properties, contributing to the development of novel treatments and medications.
Used in Research and Development:
Benzenebutanoic acid, 3-brom-.alpha.,.gamma.-dioxo-, ethyl ester is also utilized in research and development settings to explore its chemical properties and potential applications. Scientists and researchers use this compound to investigate new reaction pathways, develop innovative synthetic methods, and study its interactions with other molecules, which can lead to the discovery of new applications and uses in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 473537-92-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,3,5,3 and 7 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 473537-92:
(8*4)+(7*7)+(6*3)+(5*5)+(4*3)+(3*7)+(2*9)+(1*2)=177
177 % 10 = 7
So 473537-92-7 is a valid CAS Registry Number.
473537-92-7Relevant articles and documents
Heterocyclic substituted biphenyl compound as well as preparation method and application thereof
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Paragraph 0045; 0047; 0060-0061, (2021/08/28)
The invention discloses a heterocyclic substituted biphenyl compound as well as a preparation method and application thereof. According to the present invention, the compound can block the PD-1/PD-L1 signal pathway, and can be used as the immune checkpoint PD-1/PD-L1 small molecule inhibitor; and according to the compound disclosed by the invention, the metabolic stability is improved while the high binding rate with PD-L1 protein is maintained. A hydrophilic group is introduced to a heterocyclic ring, and the PD-1/PD-L1 inhibitory activity is improved.
Rational modification, synthesis and biological evaluation of 3,4-dihydroquinoxalin-2(1H)-one derivatives as potent and selective c-Jun N-terminal kinase 3 (JNK3) inhibitors
Dou, Xiaodong,Huang, Huixia,Jiang, Lan,Jiao, Ning,Jin, Hongwei,Liu, Zhenming,Zhang, Liangren,Zhang, Lihe,Zhu, Guiwang
, (2020/07/03)
The c-Jun N-terminal kinase 3 (JNK3) plays key roles in a wide range of diseases, including neurodegeneration diseases, inflammation diseases, cancers, cardiovascular diseases, and metabolic disorders. Previously, we have identified a lead compound, (Z)-3
PYRAZOLYL-BASED CARBOXAMIDES I AS CRAC CHANNEL INHIBITORS
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Page/Page column 63, (2014/07/23)
The Invention relates to pyrazolyl-based carboxamide compounds of formula (l) useful as ICRAC inhibitors, to pharmaceutical compositions containing these compounds and to these compounds for the use in the treatment and/or prophylaxis of diseases and/or disorders, in particular inflammatory diseases and/or inflammatory disorders.
