4736-30-5 Usage
Description
(3E)-3-[(4-hydroxyphenyl)methylidene]dihydrofuran-2(3H)-one, also known as resveratrol, is a natural phenol compound found in various plants such as grapes, berries, and peanuts. It possesses antioxidant properties and is believed to have potential health benefits, including anti-inflammatory and anticancer effects.
Used in Pharmaceutical Industry:
Resveratrol is used as a therapeutic agent for its potential in preventing heart disease and providing neuroprotective effects. Its antioxidant and anti-inflammatory properties make it a promising candidate for the development of drugs targeting various health conditions.
Used in Skincare Industry:
Resveratrol is used as an active ingredient in skincare products for its potential to improve skin health. Its anti-aging properties and ability to protect the skin from oxidative stress make it a popular choice for anti-aging and skin rejuvenation formulations.
Used in Nutraceutical Industry:
Resveratrol is used as a dietary supplement for its potential health benefits, including its antioxidant and anti-inflammatory effects. It is often included in nutraceutical products to promote overall health and well-being.
Check Digit Verification of cas no
The CAS Registry Mumber 4736-30-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,7,3 and 6 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 4736-30:
(6*4)+(5*7)+(4*3)+(3*6)+(2*3)+(1*0)=95
95 % 10 = 5
So 4736-30-5 is a valid CAS Registry Number.
4736-30-5Relevant articles and documents
Systematic Investigation into the Matsuda-Heck Reaction of α-Methylene Lactones: How Conformational Constraints Direct the β-H-Elimination Step
Schmidt, Bernd,Wolf, Felix,Ehlert, Christopher
, p. 11235 - 11249 (2016/11/28)
α-Methylene-γ-butyrolactone and α-methylene-δ-valerolactone undergo Pd-catalyzed Matsuda-Heck couplings with arene diazonium salts to α-benzyl butenolides or pentenolides, respectively, or to α-benzylidene lactones. The observed regioselectivity is strongly ring size dependent, with six-membered rings giving exclusively α-benzyl pentenolides, whereas the five-membered α-methylene lactone reacts to mixtures of regioisomers with a high proportion of (E)-α-benzylidene-γ-butyrolactones. DFT calculations suggest that the reasons for these differences are not thermodynamic but kinetic in nature. The relative energies of the conformers of the Pd σ-complexes resulting from insertion into the Pd-aryl bond were correlated with the dihedral angles between Pd and endo-β-H. This correlation revealed that in the case of the six-membered lactone an energetically favorable conformer adopts a nearly synperiplanar Pd/endo-β-H arrangement, whereas for the analogous Pd σ-complex of the five-membered lactone the smallest Pd/endo-β-H dihedral angle is observed for a conformer with a comparatively high potential energy. The optimized conditions for Matsuda-Heck arylations of exo-methylene lactones were eventually applied to the synthesis of the natural product anemarcoumarin A.