473730-88-0

Basic information

• Product Name: 3-METHYLPIPERIDIN-3-OL
• Synonyms: 3-METHYLPIPERIDIN-3-OL;3-Hydroxy-3-methylpiperidine;3-Hydroxy-3-methylpiperid...;3-methylpiperidin-3-ol hydrochloride;3-methylpiperidin-3-ol(SALTDATA: FREE);3-Methyl-3-Piperidinol;3-Piperidinol,3-methyl-
• CAS NO: 473730-88-0
• Molecular Formula: C₆H₁₃NO
• Molecular Weight: 115.18
• Mol File: 473730-88-0.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 190.977 °C at 760 mmHg
• Flash Point: 85.603 °C
• Appearance: /
• Density: 0.977 g/cm³
• Vapor Pressure: 0.142mmHg at 25°C
• Refractive Index: 1.465
• Storage Temp.: 2-8°C(protect from light)
• PKA: 14.97±0.20(Predicted)
• CAS DataBase Reference: 3-METHYLPIPERIDIN-3-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHYLPIPERIDIN-3-OL(473730-88-0)
• EPA Substance Registry System: 3-METHYLPIPERIDIN-3-OL(473730-88-0)

Safety Data

• RIDADR: UN2811
• Hazardous Substances Data: 473730-88-0(Hazardous Substances Data)

Usage

General Description

3-Methylpiperidin-3-ol is a chemical compound that belongs to the category of organic compounds known as piperidinols. It is a piperidine alkaloid with a formula of C6H13NO. 3-METHYLPIPERIDIN-3-OL is characterized by a piperidine ring which contains one hydroxyl group (-OH) and one methyl group (-CH3) as substituents. It is also recognized for its secondary alcohol properties, as it contains a secondary hydroxyl group. Although less widely studied compared to other piperidine derivatives, 3-Methylpiperidin-3-ol, due to its particular structure, might be used in chemical synthesis or as a potential bioactive molecule.

InChI:InChI=1/C6H13NO/c1-6(8)3-2-4-7-5-6/h7-8H,2-5H2,1H3

Upstream product

• 626-56-2 3-Methylpiperidine 
• 98977-36-7 3-oxo-piperidine-1-carboxylic acid tert-butyl ester 
• 1104083-27-3 tert-butyl 3-hydroxy-3-methylpiperidine-1-carboxylate 
• 6560-72-1 1-benzyl-3-methyl-piperidin-3-ol 

Downstream Products

• 1443118-58-8 (3-hydroxy-3-methylpiperidin-1-yl)(4-((4-methoxyphenyl)ethynyl)phenyl)methanone 
• 19980-02-0 (3-hydroxy-3-methylpiperidin-1-yl)(phenyl)methanone 
• 1200131-26-5 1-(4-bromobenzyl)-3-methylpiperidin-3-ol 

Relevant articles and documents

Remote C(sp3)-H Oxygenation of Protonated Aliphatic Amines with Potassium Persulfate

This letter describes the development of a method for selective remote C(sp3)-H oxygenation of protonated aliphatic amines using aqueous potassium persulfate. Protonation serves to deactivate the proximal C(sp3)-H bonds of the amine substrates and also renders the amines soluble in the aqueous medium. These reactions proceed under relatively mild conditions (within 2 h at 80 °C with amine as limiting reagent) and do not require a transition metal catalyst. This method is applicable to a variety of types of C(sp3)-H bonds, including 3°, 2°, and benzylic C-H sites in primary, secondary, and tertiary amine substrates.

2-SUBSTITUTED-ETHYNYLTHIAZOLE DERIVATIVES AND USES OF SAME

The present invention provides 2-substituted-ethynylthiazole derivatives of formula (I): wherein R1, R2 and X are as defined herein, or a pharmaceutically acceptable salt thereof; and pharmaceutical compositions and methods of using same.

QUINOLONE ANTIBACTERIAL AGENTS

Compounds of formula (I, II, III, IV, V, and VI) and methods for their preparation are disclosed. Further disclosed are methods of making biologically active compounds of formula (I) as well as pharmaceutically acceptable compositions comprising compounds of formula (I). Compounds of formula (I) as disclosed herein can be used in a variety of applications including use as antibacterial agents.