474-44-2 Usage
Description
(20S)-3alpha-amino-5alpha-pregnan-20-ol, also known as epidepride, is a chemical compound belonging to the class of pregnane steroids. It has a molecular formula of C21H37NO2 and features a pregnane backbone with an amino group at the 3alpha position and a hydroxyl group at the 20 position. (20S)-3alpha-amino-5alpha-pregnan-20-ol has been studied for its potential pharmaceutical properties, particularly as a ligand for labeling dopamine D2 and D3 receptors in the brain. Its unique structure and properties make it a promising candidate for further research and potential therapeutic applications in the future.
Uses
Used in Pharmaceutical Research:
(20S)-3alpha-amino-5alpha-pregnan-20-ol is used as a research compound for studying the interactions and functions of dopamine D2 and D3 receptors in the brain. Its ability to selectively bind to these receptors makes it a valuable tool in understanding the role of dopamine in various neurological and psychiatric disorders.
Used in Drug Development:
As a ligand for dopamine D2 and D3 receptors, (20S)-3alpha-amino-5alpha-pregnan-20-ol is used in the development of potential therapeutic agents targeting these receptors. This could lead to the creation of new drugs for the treatment of conditions such as schizophrenia, Parkinson's disease, and addiction, where dopamine dysregulation is implicated.
Used in Diagnostic Imaging:
(20S)-3alpha-amino-5alpha-pregnan-20-ol can be used as a radiotracer in diagnostic imaging techniques, such as positron emission tomography (PET), to visualize the distribution and density of dopamine D2 and D3 receptors in the brain. This can help in the diagnosis and monitoring of diseases associated with dopamine receptor abnormalities.
Used in Neuroscientific Studies:
(20S)-3alpha-amino-5alpha-pregnan-20-ol serves as a valuable research tool in neuroscientific studies, allowing researchers to investigate the role of dopamine D2 and D3 receptors in cognitive functions, emotional regulation, and reward processing. This can contribute to a better understanding of the underlying mechanisms of various neurological and psychiatric conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 474-44-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,7 and 4 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 474-44:
(5*4)+(4*7)+(3*4)+(2*4)+(1*4)=72
72 % 10 = 2
So 474-44-2 is a valid CAS Registry Number.
474-44-2Relevant articles and documents
Process for 3-amino-steroid preparation
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, (2008/06/13)
A novel process for the preparation of 3-amino-steroids of the formula STR1 wherein X is selected from the group consisting of STR2 and the wavy lines indicate that the substituents may be in the α- or β-position and their non-toxic, pharmaceutically acceptable acid addition salts in good yields and novel intermediates.
