4740-85-6

Basic information

• Product Name: 2-(4-Methoxyphenyl)-5-hydroxy-1,3-dioxane, 95%
• Synonyms: 2-(4-Methoxyphenyl)-5-hydroxy-1,3-dioxane, 95%
• CAS NO: 4740-85-6
• Molecular Formula: C₁₁H₁₄O₄
• Molecular Weight: 0
• Mol File: 4740-85-6.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(4-Methoxyphenyl)-5-hydroxy-1,3-dioxane, 95%(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Methoxyphenyl)-5-hydroxy-1,3-dioxane, 95%(4740-85-6)
• EPA Substance Registry System: 2-(4-Methoxyphenyl)-5-hydroxy-1,3-dioxane, 95%(4740-85-6)

Safety Data

• Hazardous Substances Data: 4740-85-6(Hazardous Substances Data)

Usage

Molecular Weight

244.28 g/mol

Purity

95%

Chemical Structure

A dioxane ring with a hydroxyl group (-OH) and a methoxyphenyl group (-OCH3) attached to it.

Usage

Commonly used as a reagent in organic synthesis and pharmaceutical research.

Unique Properties

The chemical structure and properties of 2-(4-Methoxyphenyl)-5-hydroxy-1,3-dioxane make it a potentially valuable compound in pharmaceutical applications.

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 56-81-5 glycerol 

Relevant articles and documents

Modified boehmite: A choice of catalyst for the selective conversion of glycerol to five-membered dioxolane

The choice of the active site and support matrix decides the activity of a catalyst. Any modifications on these will have a significant impact on the reactivity and selectivity of the catalyst. Here, we have synthesised WO3-loaded boehmite and applied it for the acetalization of a biomass-derived bulk chemical, glycerol. The well-characterized acid catalyst exhibits a selective acetalization of glycerol with good conversions into a five-membered dioxolane product. The cyclability of the catalyst up to six times along with the retention of the catalytic activity ensures the heterogeneity of the material.

Microwave rehydrated Mg-Al-LDH as base catalyst for the acetalization of glycerol

Acetalization of glycerol with aldehydes to form cyclic acetals is an industrially important reaction and is generally carried out using acid catalysts. Base catalysts such as LDH can bring about microwave-assisted acetalization of glycerol and aldehydes to form 5-membered and 6-membered cyclic acetals. Among the different LDHs used, Mg-Al-LDH was found to exhibit maximum conversion of glycerol into 5-membered cyclic acetal. Modification of Mg-Al-LDH involving calcination at 450°C and subsequent microwave-assisted rehydration showed improved glycerol conversion rate under similar reaction conditions. Rehydration of calcined Mg-Al-LDH by microwave irradiation was found to result in LDH regaining its layered structure with higher basicity possibly exposing more hydroxyl ions responsible for basicity. Multiple use of methanol washed spent catalyst showed good repeatability for conversion up to three cycles which subsequently showed a marginal decrease in the conversion. Further dehydration followed by rehydration of the spent LDH catalyst under microwave irradiation was found to rejuvenate the catalytic activity to its initial level.

Room temperature acetalization of glycerol to cyclic acetals over anchored silicotungstates under solvent free conditions

Heterogeneous catalysts comprising of parent Keggin type silicotungstate as well as monolacunary silicotungstate anchored to MCM-41 were synthesized and characterized by several physicochemical methods. A solvent free green route towards valorisation of glycerol via acetalization with benzaldehyde has been proposed. Both the catalysts showed very good activity as well as selectivity towards dioxolane derivatives within a short reaction time and at room temperature. The tuning of the acidity of the parent silicotungstate leads to an increase in the selectivity towards 1,3-dioxolane. The catalysts were also recycled up to four times without any significant loss in the conversion. The excellent performance of these mesoporous catalysts is attributed to their combination of acidity, wide pores and large specific surface area. the Partner Organisations 2014.