47424-13-5

Basic information

• Product Name: Benzoic acid, 4,4'-sulfonylbis-, diethyl ester
• CAS NO: 47424-13-5
• Molecular Formula: C18H18O6S
• Molecular Weight: 362.403
• Mol File: 47424-13-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4,4'-sulfonylbis-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4,4'-sulfonylbis-, diethyl ester(47424-13-5)
• EPA Substance Registry System: Benzoic acid, 4,4'-sulfonylbis-, diethyl ester(47424-13-5)

Safety Data

• Hazardous Substances Data: 47424-13-5(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 2449-35-6 bis(4-carboxyphenyl)sulfone 
• 599-66-6 bis(4-methylphenyl) sulfone 
• 181148-10-7 Bi(p-C₂H₅OOCC₆H₄)3 
• 3965-53-5 4,4'-dicarbomethoxydiphenyl sulfone 

Downstream Products

• 27719-11-5 p,p’-dihydrazinocarbonyldiphenylsulfone 
• 132475-42-4 C₃₂H₂₂Cl₂N₆O₁₀S 
• 132475-41-3 C₃₂H₂₂Cl₂N₆O₁₀S 
• 132475-40-2 C₃₄H₂₈Cl₂N₄O₁₀S 
• 132475-39-9 C₃₆H₃₂Cl₂N₄O₁₀S 
• 132475-36-6 C₃₂H₂₀Cl₆N₄O₆S 
• 132500-78-8 C₃₄H₂₈Cl₂N₄O₁₀S 
• 132475-35-5 C₃₂H₂₀Cl₆N₄O₆S 
• 132475-37-7 C₃₄H₂₈Cl₂N₄O₈S 
• 132475-38-8 C₃₄H₂₈Cl₂N₄O₈S 
• 132475-43-5 C₃₂H₂₄Cl₂N₄O₈S 
• 132475-33-3 C₃₂H₂₂Cl₄N₄O₆S 
• 132475-44-6 C₃₂H₂₄Cl₂N₄O₈S 
• 132475-34-4 C₃₂H₂₂Cl₄N₄O₆S 

Relevant articles and documents

Sulfonylation of Bismuth Reagents with Sulfinates or SO2through BiIII/BiV Intermediates

Studies to explore the catalytic activities of main-group elements are attractive. We report here our study of sulfonylation of bismuth reagents with sulfinates or SO2 surrogates. Under oxidative conditions, triarylbismuthines and sulfinates were transformed into diaryl sulfones. A transition-metal-like two-electron redox process at the Bi center was achieved in this reaction. Sulfur dioxide generated in situ can also replace sulfinates to deliver the corresponding symmetric diaryl sulfones. A rational mechanism for this reaction was also proposed that involves a Bi(III)-Bi(V) manifold.

Kepner-Tregoe decision analysis as a tool to aid route selection. Part 2. Application to AZD7545, a PDK inhibitor

Kepner-Tregoe decision analysis was formally used as an aid to route selection, as outlined in the preceding paper. Over 40 paper routes were assessed for suitability for both immediate and longer term manufacture of AZD7545, a compound in the early stages of development. Eight routes were then investigated in full in the laboratory, and a further four in part, over a period of 3-4 months. From this exercise, the preferred long-term manufacturing route was identified before the first pilot scale manufacture had been completed. This route selection exercise worked well in this case where a large number of potential routes had to be considered using limited resources. It was also an effective means of bringing some long-term manufacturing issues to the fore at an early stage in development.