47441-33-8

Basic information

• Product Name: N₁,N₁-diethyl-N₄-(1,2,3,4-tetrahydroacridin-9-yl)pentane-1,4-diamine
• Synonyms: N₁,N₁-diethyl-N₄-(1,2,3,4-tetrahydroacridin-9-yl)pentane-1,4-diamine
• CAS NO: 47441-33-8
• Molecular Weight: 339.524
• Mol File: 47441-33-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N₁,N₁-diethyl-N₄-(1,2,3,4-tetrahydroacridin-9-yl)pentane-1,4-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: N₁,N₁-diethyl-N₄-(1,2,3,4-tetrahydroacridin-9-yl)pentane-1,4-diamine(47441-33-8)
• EPA Substance Registry System: N₁,N₁-diethyl-N₄-(1,2,3,4-tetrahydroacridin-9-yl)pentane-1,4-diamine(47441-33-8)

Safety Data

• Hazardous Substances Data: 47441-33-8(Hazardous Substances Data)

Upstream product

• 5396-30-5 9-chloro-1,2,3,4-tetrahydroacridine 
• 140-80-7 5-diethylamino-2-pentylamine 

Relevant articles and documents

Pd-catalyzed amination as an alternative to nucleophilic aromatic substitution for the synthesis of N-alkyltacrines and analogs

A reliable Pd-catalyzed amination protocol is described for the synthesis of N-alkyltacrines and analogs. The Josiphos ligand CyPFtBu was found to provide optimum yields: 16 examples are given. Compared to the typical high-temperature nucleophilic aromatic substitution (NAS) routes, Pd-catalyzed aminations proceed at significantly lower reaction temperatures, and enable the synthesis of otherwise inaccessible products.