474430-67-6Relevant articles and documents
Novel inhibitors of fatty acid amide hydrolase
Sit,Conway, Charlie,Bertekap, Robert,Xie, Kai,Bourin, Clotilde,Burris, Kevin,Deng, Hongfeng
, p. 3287 - 3291 (2008/02/09)
A class of bisarylimidazole derivatives are identified as potent inhibitors of the enzyme fatty acid amide hydrolase (FAAH). Compound 17 (IC50 = 2 nM) dose-dependently (0.1-10 mg/kg, iv) potentiates the effects of exogenous anandamide (1 mg/kg,