474710-80-0

Basic information

• Product Name: 4-Quinazolinecarboxylic acid, 6-bromo-, ammonium salt
• Synonyms: 4-Quinazolinecarboxylic acid, 6-bromo-, ammonium salt;6-Bromo-4-quinazolinecarboxylic acid ammonium salt;6-bromoquinazoline-4-carboxylic acid, ammonia salt;aMMonia salt;AMMoniuM 6-broMoquinazoline-4-carboxylate
• CAS NO: 474710-80-0
• Molecular Formula: C9H8BrN3O2
• Molecular Weight: 270.08
• Product Categories: CHIRAL CHEMICALS
• Mol File: 474710-80-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 497.1 °C at 760 mmHg
• Flash Point: 254.4 °C
• Appearance: /
• Density: 1.824g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.722
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 4-Quinazolinecarboxylic acid, 6-bromo-, ammonium salt(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Quinazolinecarboxylic acid, 6-bromo-, ammonium salt(474710-80-0)
• EPA Substance Registry System: 4-Quinazolinecarboxylic acid, 6-bromo-, ammonium salt(474710-80-0)

Safety Data

• Hazardous Substances Data: 474710-80-0(Hazardous Substances Data)

Usage

General Description

4-Quinazolinecarboxylic acid, 6-bromo-, ammonium salt is a chemical compound with the molecular formula C9H8BrN3O2. It is a quinazoline derivative with a carboxylic acid group and a bromine atom at the 6 position. 4-Quinazolinecarboxylic acid, 6-bromo-, ammonium salt is usually found in the form of an ammonium salt, which ensures its stability and solubility in water. It is commonly used in the pharmaceutical industry as a building block for the synthesis of various biologically active compounds, including potential drug candidates. Its unique structure and properties make it a valuable intermediate in organic synthesis and drug development.

InChI:InChI=1/C9H5BrN2O2/c10-5-1-2-7-6(3-5)8(9(13)14)12-4-11-7/h1-4H,(H,13,14)

Upstream product

• 474710-79-7 5-bromo-N-formylisatin 

Downstream Products

• 474710-78-6 methyl 6-bromoquinazolin-4-carboxylate 

Relevant articles and documents

NITROGENOUS FUSED?RING COMPOUND HAVING PYRAZOLYL GROUP AS SUBSTITUENT AND MEDICINAL COMPOSITION THEREOF

The present invention provides a compound having an excellent inhibitory action on activation of STAT6 and a pharmaceutical composition thereof. Inparticular, it provides a compound represented by the following formula (I), a salt thereof or a hydrate of them. In the formula, X represents a nitrogen-containing condensed aromatic heterocyclic group such as imidazo[1,2-a]pyridine, benzimidazole, quinazoline, quinoline, or 2,1-benzisoxazole and has (R4)n as substituent groups; Y represents a C3-8 cycloalkyl group, C4-8 cycloalkenyl group, 5- to 14-membered non-aromatic heterocyclic group, C6-14 aromatic hydrocarbon cyclic group or 5- to 14-membered aromatic heterocyclic group; n in (R4)n is 0, 1, 2 or 3, and Z groups independently represent (1) hydrogen atom, (2) amino group, (3) halogen atom, (4) hydroxyl group, (5) nitro group, (6) cyano group, (7) azido group, (8) formyl group, (9) hydroxyamino group, (10) sulfamoyl group, (11) guanodino group, (12) oxo group, (13) C2-6 alkenyl group, (14) C1-6 alkoxy group, (15) C1-6 alkylhydroxyamino group, (16) halogenated C1-6 alkyl group, (17) halogenated C2-6 alkenyl group, (18) (i) C3-7cycloalkyl group, (ii) C3-7cycloalkenyl group, (iii) 5- to 14-membered non-aromatic heterocyclic group, each of which may have one or more substituent groups Q, or (19) formula -M1-M2-M3, R1 represents (1) hydrogen atom, (2) halogen atom, (3) hydroxyl group, (4) nitro group, (5) cyano group, (6) halogenated C1-6 alkyl group, (7) C2-6 alkyl group substituted with a hydroxyl or cyano group, (8) C2-6 alkenyl group, or (9) formula -L1-L2-L3, and R2 represents a hydrogen atom or a protecting group; and R3 represents a hydrogen atom, halogen atom, cyano group, amino group, C1-4 alkyl group or halogenated C1-4 alkyl group.