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475-25-2

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475-25-2 Usage

Description

HEMATEIN, also known as hematoxylin, is an organic heterotetracyclic compound with the chemical formula C16H18O5. It is a dark brown crystalline powder that carries four hydroxy substituents at positions 3, 4, 6a, and 10. HEMATEIN is derived from the oxidation of hematoxylin and is known for its various applications in different industries.

Uses

Used in Medical and Scientific Research:
HEMATEIN is used as a stain for the cell nuclei of animal tissue, particularly in histology and cytology. It is an essential tool for visualizing and studying cellular structures, making it a valuable asset in medical and scientific research.
Used in Pharmaceutical Industry:
HEMATEIN serves as a CK2 inhibitor, an antineoplastic agent, a TNFa inhibitor, and an anti-inflammatory substance. These properties make it a potential candidate for the development of new drugs and therapies in the pharmaceutical industry.
Used in Dyes and Metabolites:
HEMATEIN is also used in the production of dyes and metabolites, with its color index being 75290. This application highlights its versatility and potential for use in various industrial processes.
Used in Staining Myelin Sheaths and Nerve Fibers:
HEMATEIN is suggested to possess use as a stain for myelin sheaths and nerve fibers, which can be beneficial for studying the nervous system and related conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 475-25-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,7 and 5 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 475-25:
(5*4)+(4*7)+(3*5)+(2*2)+(1*5)=72
72 % 10 = 2
So 475-25-2 is a valid CAS Registry Number.
InChI:InChI=1/C16H12O6/c17-10-2-1-8-13-9-4-12(19)11(18)3-7(9)5-16(13,21)6-22-15(8)14(10)20/h1-3,17,20-21H,4-6H2/t16-/m1/s1

475-25-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 3,4,6a,10-tetrahydroxy-6,7-dihydroindeno[2,1-c]chromen-9-one

1.2 Other means of identification

Product number -
Other names Haematein

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:475-25-2 SDS

475-25-2Synthetic route

haematoxylin

haematoxylin

haematein
475-25-2

haematein

Conditions
ConditionsYield
With ammonia Behandeln mit Essigsaeure;
With ammonia at 130℃;
With iodine; mercury(II) oxide
hematoxylin
17647-60-8

hematoxylin

A

hydroxyhematoxylin

hydroxyhematoxylin

B

haematein
475-25-2

haematein

Conditions
ConditionsYield
With water Mechanism; Electrolysis;
haematein
475-25-2

haematein

hydroxyhematoxylin

hydroxyhematoxylin

Conditions
ConditionsYield
With water Electrolysis;7%
dimethyl sulfate
77-78-1

dimethyl sulfate

haematein
475-25-2

haematein

KOH-solution

KOH-solution

A

haematein-tetramethyl ether

haematein-tetramethyl ether

B

pentamethyl-dihydrohaemateinol

pentamethyl-dihydrohaemateinol

Conditions
ConditionsYield
yttrium(III) chloride
10361-92-9

yttrium(III) chloride

haematein
475-25-2

haematein

Y(C16H8O6)2(5-)*4H(1+)

Y(C16H8O6)2(5-)*4H(1+)

Conditions
ConditionsYield
In water
lead(II) nitrate

lead(II) nitrate

haematein
475-25-2

haematein

2Pb(2+)*C16H8O6(4-)*4H2O={Pb2(C16H8O6)}*4H2O

2Pb(2+)*C16H8O6(4-)*4H2O={Pb2(C16H8O6)}*4H2O

Conditions
ConditionsYield
In ammonia addn. of aq. Pb(NO3)2-soln. to aq. ammoniacal soln. of C16H12O6;; pptn.;
silver nitrate

silver nitrate

haematein
475-25-2

haematein

silver(I) hematein complex

silver(I) hematein complex

Conditions
ConditionsYield
In ethanol
lead acetate
301-04-2

lead acetate

haematein
475-25-2

haematein

hematein lead(II) complex

hematein lead(II) complex

Conditions
ConditionsYield
In ethanol
gadolinium(III) chloride

gadolinium(III) chloride

haematein
475-25-2

haematein

hematein gadolinium(III) complex

hematein gadolinium(III) complex

Conditions
ConditionsYield
In ethanol

475-25-2Upstream product

475-25-2Downstream Products

475-25-2Relevant articles and documents

-

Hummel,Perkin,A. G.

, (1882)

-

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