475294-87-2

Basic information

• Product Name: (2S,3R)-2-methyl-4-nitro-3-phenylbutanal
• Synonyms: (2S,3R)-2-methyl-4-nitro-3-phenylbutanal
• CAS NO: 475294-87-2
• Molecular Weight: 207.229
• Mol File: 475294-87-2.mol
• Article Data: 77

Chemical Properties

• CAS DataBase Reference: (2S,3R)-2-methyl-4-nitro-3-phenylbutanal(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3R)-2-methyl-4-nitro-3-phenylbutanal(475294-87-2)
• EPA Substance Registry System: (2S,3R)-2-methyl-4-nitro-3-phenylbutanal(475294-87-2)

Safety Data

• Hazardous Substances Data: 475294-87-2(Hazardous Substances Data)

Upstream product

• 102-96-5 (2-nitroethenyl)benzene 
• 123-38-6 propionaldehyde 
• 5153-67-3 nitrostyrene 
• 329969-56-4 (4-Methoxy-phenyl)-((Z)-(3S,4R)-3-methyl-5-nitro-4-phenyl-pent-1-enyl)-carbamic acid tert-butyl ester 
• 3156-37-4 4-bromo-β-nitrostyrene 
• 123-72-8 butyraldehyde 
• 1273321-70-2 C₁₃H₁₇NO₄ 
• 1207841-27-7 C₁₃H₁₅NO₄ 
• 1273321-49-5 C₁₃H₁₅NO₄ 
• 590-86-3 isovaleraldehyde 

Downstream Products

• 474925-05-8 3-allyl-3-methyl-2-oxo-4-phenyl-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 474925-03-6 3-methyl-2-oxo-4-phenyl-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 474924-94-2 3-methyl-4-phenyl-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 474925-61-6 2-methyl-4-nitro-3-phenyl-butyric acid methyl ester 
• 474924-91-9 3-methyl-4-phenyl-pyrrolidin-2-one 

Relevant articles and documents

Indolinol-catalyzed asymmetric Michael reaction of aldehydes to nitroalkenes in brine

(2S,3aS,7aS)-Perhydroindolinol A facilitated the reaction of a wide range of aldehyde and nitroalkene substrates to provide Michael adducts with excellent enantioselectivities (up to 98% ee), excellent yields and high diastereoselectivities (syn/anti up t

Environmental modulation of chiral prolinamide catalysts for stereodivergent conjugate addition

Synthetic chiral catalysts generally rely on proximal functional groups or ligands for chiral induction. Enzymes often employ environmental chirality to achieve stereoselectivity. Environmentally controlled catalysis has benefits such as size and shape se

Calcium carbonate as heterogeneous support for recyclable organocatalysts

The controlled synthesis of calcium carbonate particles surface-functionalized with azido groups and its subsequent copper-catalyzed alkyne-azide cycloaddition (CuAAC) reactions with organocatalysts bearing alkyne anchors allowed the preparation of novel catalytic materials. A calcium carbonate-supported α,α-diarylprolinol silyl ether prepared in this manner catalyzes Michael addition of aldehydes to trans-β-nitrostyrenes with very high diastereo- and enantioselectivity. The immobilized catalyst can be recovered by simple decantation and reused. In addition, this heterogeneous catalytic system can also be adapted to continuous-flow operation, affording a five-fold productivity increase in comparison with the batch process.

Asymmetric Organocatalysis Accelerated via Self-Assembled Minimal Structures

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