4754-26-1 Usage
Description
2-Ethylcyclohexa-2,5-diene-1,4-dione is an organic compound characterized by its unique molecular structure, featuring a cyclohexane ring with a diene system and an ethyl group attached to the second carbon. It also contains two carbonyl groups at the first and fourth positions, which contribute to its chemical properties and potential applications.
Uses
Used in Chemical Synthesis:
2-Ethylcyclohexa-2,5-diene-1,4-dione is used as an intermediate in the synthesis of various organic compounds, particularly those with pharmaceutical or industrial applications. Its unique structure allows for further functionalization and modification, making it a versatile building block in organic chemistry.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-ethylcyclohexa-2,5-diene-1,4-dione is used as a key component in the development of new drugs. Its chemical properties enable it to interact with biological targets, potentially leading to the creation of novel therapeutic agents.
Used in Arthropod Defense:
2-Ethylcyclohexa-2,5-diene-1,4-dione is found in the defensive secretions of certain arthropods, such as the European earwig Forficula auricularia. It exhibits biological activity against both Gram-positive and Gram-negative bacteria, as well as entomopathogenic fungi, providing a natural defense mechanism for these organisms.
Used in Antimicrobial Applications:
Due to its antimicrobial properties, 2-ethylcyclohexa-2,5-diene-1,4-dione can be used as an antimicrobial agent in various applications, such as in the development of new antibiotics or as a component in disinfectants and sanitizers. Its ability to target and inhibit the growth of bacteria and fungi makes it a promising candidate for these applications.
Synthesis Reference(s)
Tetrahedron Letters, 26, p. 819, 1985 DOI: 10.1016/S0040-4039(00)61936-6
Check Digit Verification of cas no
The CAS Registry Mumber 4754-26-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,7,5 and 4 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 4754-26:
(6*4)+(5*7)+(4*5)+(3*4)+(2*2)+(1*6)=101
101 % 10 = 1
So 4754-26-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H8O2/c1-2-6-5-7(9)3-4-8(6)10/h3-5H,2H2,1H3
4754-26-1Relevant articles and documents
Catalytic asymmetric [2+2] cycloaddition between quinones and fulvenes and a subsequent stereoselective isomerization to 2,3-dihydrobenzofurans
Zheng, Haifeng,Xu, Chaoran,Wang, Yan,Kang, Tengfei,Liu, Xiaohua,Lin, Lili,Feng, Xiaoming
supporting information, p. 6585 - 6588 (2017/07/10)
The catalytic enantioselective [2+2] cycloaddition between quinones and fulvenes was achieved, for the first time, by the use of a chiral copper(ii) complex catalyst. The transformation afforded a series of enantiomerically enriched [6,4,5]-tricyclic cyclobutane derivatives in good yields with excellent regio- and stereoselectivities. Furthermore, the [2+2] adducts could be easily converted into formal [3+2] adducts efficiently and stereoselectively.
Substituent effects in the oxidation of 2-alkyl-1,4-dialkoxybenzenes with ceric ammonium nitrate
Love, Brian E.,Simmons, Alexander L.
, p. 5712 - 5715 (2016/11/29)
Increased steric size of alkyl groups and the presence of coordinating atoms on alkoxy groups have both been found to contribute to decreasing yields of diquinones upon reaction of 2-alkyl-1,4-dialkoxybenzenes with CAN. The overall hydrophilicity of the substrates does not appear to be a significant factor in determining the diquinone yield for these reactions.
Chemo- and regioselective direct hydroxylation of arenes with hydrogen peroxide catalyzed by a divanadium-substituted phosphotungstate
Kamata, Keigo,Yamaura, Taiyo,Mizuno, Noritaka
supporting information; scheme or table, p. 7275 - 7278 (2012/08/28)
Peroxide in, phenol out: The catalyst [-PW10O38V 2(μ-OH)2]3- showed high activity in the hydroxylation of various aromatic compounds with aqueous H2O 2. The system was regioselective, producing para-phenols from monosubstituted benzene derivatives. Furthermore, alkylarenes with reactive side-chain Ca spa 3-H bonds could be chemoselectively hydroxylated without significant formation of side-chain oxygenated products. Copyright
